Evaluation of bone metastases from breast cancer by bone scintigraphy and positron emission tomography/computed tomography imaging

Evaluation of bone metastases from breast cancer by bone scintigraphy and positron emission tomography/computed tomography imaging

Author Pires, Ary O. Google Scholar
Borges, Umbelina S. Google Scholar
Lopes-Costa, Pedro V. Google Scholar
Gebrim, Luiz H. Autor UNIFESP Google Scholar
Silv, Benedito B. da Google Scholar
Institution Univ Fed Piaui
Universidade Federal de São Paulo (UNIFESP)
Abstract Objective: the aim of this study was to compare bone scintigraphy (BS) and positron emission tomography/computed tomography (PET/CT) for the detection of bone metastases from breast cancer.Study design: Twenty patients with breast cancer and bone pain were submitted to both bone scintigraphy and 18-F-fluorodeoxyglucose PET/CT imaging between July 2012 and June 2013. Scintigraphy was performed following an intravenous injection of technetium-99m-methylene diphosphonate (99mTc-MDP) around 10 days before the PET/CT scan, performed using an intravenous injection of 18-F-fluorodeoxyglucose followed by whole-body computed tomography (CT) to characterize metastases by both methods. Student's t-test for paired samples was used in the comparative data analysis, with significance at p < 0.05.Results: CT identified 429 metastatic implants in the 20 patients, with scintigraphy showing 244 of these lesions (57%) and PET/CT showing 307 (72%); however, there was no statistically significant difference between the mean number of lesions detected per patient with the two imaging modalities (p = 0.367).Conclusion: in the present study, no difference was found between PET/CT and bone scintigraphy in the detection of bone metastases from breast cancer. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
Keywords Breast
Cancer
Bone metastases
Bone scintigraphy
PET/CT
Language English
Date 2014-09-01
Published in European Journal of Obstetrics & Gynecology and Reproductive Biology. Amsterdam: Elsevier B.V., v. 180, p. 138-141, 2014.
ISSN 0301-2115 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 138-141
Origin http://dx.doi.org/10.1016/j.ejogrb.2014.06.021
Access rights Closed access
Type Article
Web of Science ID WOS:000343384700028
URI http://repositorio.unifesp.br/handle/11600/38161

Show full item record




File

File Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Search


Browse

Statistics

My Account