Structure-Function Correlations in Glaucoma Using Matrix and Standard Automated Perimetry Versus Time-Domain and Spectral-Domain OCT Devices

Structure-Function Correlations in Glaucoma Using Matrix and Standard Automated Perimetry Versus Time-Domain and Spectral-Domain OCT Devices

Author Pinto, Luciano Moreira Autor UNIFESP Google Scholar
Costa, Elaine Fiod Autor UNIFESP Google Scholar
Melo Jr., Luiz Alberto Soares de Autor UNIFESP Google Scholar
Gross, Paula Blasco Autor UNIFESP Google Scholar
Sato, Eduardo Toshio Autor UNIFESP Google Scholar
Almeida, Andrea Pereira Autor UNIFESP Google Scholar
Maia, Andre Autor UNIFESP Google Scholar
Paranhos Junior, Augusto Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract PURPOSE. We examined the structure-function relationship between two perimetric tests, the frequency doubling technology (FDT) matrix and standard automated perimetry (SAP), and two optical coherence tomography (OCT) devices (time-domain and spectral-domain).METHODS. This cross-sectional study included 97 eyes from 29 healthy individuals, and 68 individuals with early, moderate, or advanced primary open-angle glaucoma. the correlations between overall and sectorial parameters of retinal nerve fiber layer thickness (RNFL) measured with Stratus and Spectralis OCT, and the visual field sensitivity obtained with FDT matrix and SAP were assessed. the relationship also was evaluated using a previously described linear model.RESULTS. the correlation coefficients for the threshold sensitivity measured with SAP and Stratus OCT ranged from 0.44 to 0.79, and those for Spectralis OCT ranged from 0.30 to 0.75. Regarding FDT matrix, the correlation ranged from 0.40 to 0.79 with Stratus OCT and from 0.39 to 0.79 with Spectralis OCT. Stronger correlations were found in the overall measurements and the arcuate sectors for both visual fields and OCT devices. A linear relationship was observed between FDT matrix sensitivity and the OCT devices. the previously described linear model fit the data from SAP and the OCT devices well, particularly in the inferotemporal sector.CONCLUSIONS. the FDT matrix and SAP visual sensitivities were related strongly to the RNFL thickness measured with the Stratus and Spectralis OCT devices, particularly in the overall and arcuate sectors.
Keywords glaucoma posterior segment
automated perimetry
optical coherence tomography
Language English
Sponsor Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Date 2014-05-01
Published in Investigative Ophthalmology & Visual Science. Rockville: Assoc Research Vision Ophthalmology Inc, v. 55, n. 5, p. 3074-3080, 2014.
ISSN 0146-0404 (Sherpa/Romeo, impact factor)
Publisher Assoc Research Vision Ophthalmology Inc
Extent 3074-3080
Origin http://dx.doi.org/10.1167/iovs.13-13664
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000339484800035
URI http://repositorio.unifesp.br/handle/11600/37692

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