Minimum Evaporation Model of Dermatological Delivery Systems. Lamellar Liquid Crystal Formulations Containing Brazilian Nut (Bertholletia excelsa HBK) Vegetable Oil and Guarana Glycolic Extract

Minimum Evaporation Model of Dermatological Delivery Systems. Lamellar Liquid Crystal Formulations Containing Brazilian Nut (Bertholletia excelsa HBK) Vegetable Oil and Guarana Glycolic Extract

Author Monteiro e Silva, Silas Arandas Autor UNIFESP Google Scholar
Costa Valarini, Michele Fernanda Google Scholar
Chorilli, Marlus Google Scholar
Friberg, Stig E. Google Scholar
Leonardi, Gislaine Ricci Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Univ Metodista Piracicaba
São Paulo State Univ
NTNU
Abstract Formulations with lyotropic liquid crystals were prepared from a Brazilian nut vegetable oil, guarana extract and combination of sorbitan monooleate (Span 80) and sorbitan monolaurate ethoxylate EO 20 (Tween 20) in the ratio 1: 3 (surfactant component) and their physical-chemical aspects and rheological properties were determined. Compositions with liquid crystals were found in the pseudoternary diagram in a surfactant range of 70-90% and polarized light microscopy, small-angle x-ray scattering (SAXS) showed them to be lamellar. the preparations were furthermore characterized rheologically by shear stress shear rate sweeps finding plastic and pseudoplastic behavior without thixotropy. Electric conductivity and pH measurements demonstrated a potential for future application as dermatological delivery system of the active compounds in the Bertholletia excelsa and Paullinia cupana.
Keywords Cosmetics
dermatological formulations
liquid crystals
rheology
vegetable oils
Language English
Sponsor Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Date 2014-01-01
Published in Journal of Dispersion Science and Technology. Philadelphia: Taylor & Francis Inc, v. 35, n. 8, p. 1191-1199, 2014.
ISSN 0193-2691 (Sherpa/Romeo, impact factor)
Publisher Taylor & Francis Inc
Extent 1191-1199
Origin http://dx.doi.org/10.1080/01932691.2013.826586
Access rights Closed access
Type Article
Web of Science ID WOS:000337632100016
URI http://repositorio.unifesp.br/handle/11600/37263

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