Successful Intra-arterial Thrombolysis in a Patient with an Intracranial Meningioma

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dc.contributor.author Baiense, Robson Fantinato [UNIFESP]
dc.contributor.author Abrahao, Agessandro [UNIFESP]
dc.contributor.author Ricarte, Irapua F. [UNIFESP]
dc.contributor.author Fukuda, Thiago G. [UNIFESP]
dc.contributor.author Oliveira, Ricardo A. [UNIFESP]
dc.contributor.author Silva, Gisele S. [UNIFESP]
dc.contributor.author Costa, Maristela
dc.contributor.author Teixeira, Manoel J.
dc.date.accessioned 2016-01-24T14:34:40Z
dc.date.available 2016-01-24T14:34:40Z
dc.date.issued 2013-11-01
dc.identifier http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2013.05.009
dc.identifier.citation Journal of Stroke & Cerebrovascular Diseases. Amsterdam: Elsevier B.V., v. 22, n. 8, p. E658-E660, 2013.
dc.identifier.issn 1052-3057
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/36946
dc.description.abstract Alteplase (recombinant tissue plasminogen activator [rt-PA]) label approval by the Food and Drug Administration remarks the contraindication of its use with known intracranial neoplasm because of potential bleeding complications. Despite this concern, the real risk of intracerebral bleeding in patients with intracranial neoplasms treated with rt-PA is unknown, and there are few reports of thrombolysis in patients with brain tumors. We report a case of a 78-year-old man who was seen in our emergency department within 2 hours from sudden onset of aphasia, right-sided hemiplegia, hypoesthesia, and homonymous hemianopsia. the National Institutes of Health Stroke Scale (NIHSS) score at admission was 20. Intra-arterial thrombolysis was performed with administration of .3 mg/kg of alteplase combined with mechanical thrombectomy. At discharge, his NIHSS score was 1, and after 90 days, his modified Rankin score was 1. To our knowledge, this is the first report of intra-arterial thrombolysis in a patient with acute ischemic stroke with an intracranial tumor. en
dc.format.extent E658-E660
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof Journal of Stroke & Cerebrovascular Diseases
dc.rights Acesso restrito
dc.subject Intra-arterial thrombolysis en
dc.subject meningioma en
dc.subject intracranial neoplasm en
dc.subject acute ischemic stroke en
dc.subject mechanical thrombectomy en
dc.subject intracranial hemorrhage en
dc.title Successful Intra-arterial Thrombolysis in a Patient with an Intracranial Meningioma en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Hosp Coracao
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Hosp Coracao, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Neurol & Neurocirurgia, BR-04039000 São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Neurol & Neurocirurgia, BR-04039000 São Paulo, Brazil
dc.identifier.doi 10.1016/j.jstrokecerebrovasdis.2013.05.009
dc.description.source Web of Science
dc.identifier.wos WOS:000327719000066



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