Brain health and cognitive and mood disorders in ageing women

Brain health and cognitive and mood disorders in ageing women

Author Silva, Ivaldo Autor UNIFESP Google Scholar
Naftolin, Frederick Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
NYU
Abstract Improved medical, economic and socio-cultural conditions have increased life expectancy, especially for women. the incidence of hypertension, diabetes mellitus, psychiatric and degenerative brain diseases, especially stroke and dementia, are more frequently seen in older people. Each of these conditions can separately, or in combination, result in similar signs and symptoms of cognition, memory, mood and motor function disorders. Therefore, it is important to understand the effects of normal ovarian ageing and the menopause on the nervous system, as well as the hallmarks of disease entities; many of these are described here. Also, the complexity of these issues is increased by the similarity of their effects to those of the polypharmacy and metabolic imbalances that are common in this population. These are complex issues, and it may be difficult and time-consuming to discern between normal brain functional changes and specific pathology in practice. Early evaluation of correctable possibilities, including imaging studies, may be key to management. Referral to specialists for diagnosis before starting clinical treatment is useful to address these issues. (C) 2013 Elsevier B.V. All rights reserved.
Keywords bain
cognition
woman
sexual hormone
aging
Language English
Date 2013-10-01
Published in Best Practice & Research Clinical Obstetrics & Gynaecology. Oxford: Elsevier B.V., v. 27, n. 5, p. 661-672, 2013.
ISSN 1521-6934 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 661-672
Origin http://dx.doi.org/10.1016/j.bpobgyn.2013.06.005
Access rights Closed access
Type Article
Web of Science ID WOS:000325117900003
URI http://repositorio.unifesp.br/handle/11600/36809

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