Nutritional status and metabolic disorders in HIV-exposed uninfected prepubertal children

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dc.contributor.author Claudio, Cristiane Chiantelli [UNIFESP]
dc.contributor.author Patin, Rose Vega [UNIFESP]
dc.contributor.author Palchetti, Cecilia Zanin [UNIFESP]
dc.contributor.author Machado, Daisy Maria [UNIFESP]
dc.contributor.author Menezes Succi, Regina Celia de [UNIFESP]
dc.contributor.author Oliveira, Fernanda Luisa Ceragioli [UNIFESP]
dc.date.accessioned 2016-01-24T14:31:57Z
dc.date.available 2016-01-24T14:31:57Z
dc.date.issued 2013-07-01
dc.identifier http://dx.doi.org/10.1016/j.nut.2013.01.019
dc.identifier.citation Nutrition. New York: Elsevier B.V., v. 29, n. 7-8, p. 1020-1023, 2013.
dc.identifier.issn 0899-9007
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/36497
dc.description.abstract Objective: the objective of the study was to assess the nutritional status and metabolic alterations in HIV-exposed uninfected (HIVe) children compared with HIV-unexposed (HIVn) children.Methods: A cross-sectional study was carried out with 76 children distributed into two groups: HIVe (n = 31) and HIVn (n = 45). Biochemical data (hematologic test, lipid profile, insulin resistance, hepatic profile, and C-reactive protein) were evaluated. Anthropometric parameters and body composition analyses were performed.Results: the groups were similar regarding body mass index-for-age z-scores (P = 0.297) and height-for-age z-scores (P = 0.666). HIVe had a higher dyslipidemia prevalence (38.7% versus 11.1%; P = 0.010), altered total cholesterol (TC) values (19.4% versus 2.2%; P = 0.016) higher LDL-C mean levels (97.8 mg/dl versus 86 mg/dl; P = 0.028), borderline low-density lipoprotein cholesterol (LDL-C) (40% versus 14%; P = 0.011) and TC (41.9% versus 20%; P = 0.038) compared with HIVn.Conclusion: Despite the similar nutritional status between groups, our data clearly demonstrated a higher prevalence of dyslipidemia, altered TC, higher LDL-C levels and also LDL-C and TC borderline values in HIVe children. (C) 2013 Elsevier Inc. All rights reserved. en
dc.format.extent 1020-1023
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof Nutrition
dc.rights Acesso restrito
dc.subject Dyslipidemia en
dc.subject HIV en
dc.subject Child en
dc.subject Prophylaxis en
dc.subject Nutrition en
dc.title Nutritional status and metabolic disorders in HIV-exposed uninfected prepubertal children en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation UNIFESP EPM, Dept Pediat, Div Nutr, São Paulo, Brazil
dc.description.affiliation UNIFESP EPM, Dept Pediat, Div Pediat Infect Dis, São Paulo, Brazil
dc.description.affiliationUnifesp UNIFESP EPM, Dept Pediat, Div Nutr, São Paulo, Brazil
dc.description.affiliationUnifesp UNIFESP EPM, Dept Pediat, Div Pediat Infect Dis, São Paulo, Brazil
dc.identifier.doi 10.1016/j.nut.2013.01.019
dc.description.source Web of Science
dc.identifier.wos WOS:000321029700016



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