Pediatric allergy and immunology in Brazil

Pediatric allergy and immunology in Brazil

Author Rosario-Filho, Nelson A. Google Scholar
Jacob, Cristina M. Google Scholar
Sole, Dirceu Autor UNIFESP Google Scholar
Condino-Neto, Antonio Google Scholar
Arruda, Luisa K. Google Scholar
Costa-Carvalho, Beatriz Autor UNIFESP Google Scholar
Cocco, Renata R. Autor UNIFESP Google Scholar
Camelo-Nunes, Ines Autor UNIFESP Google Scholar
Chong-Neto, Herberto J. Google Scholar
Wandalsen, Gustavo F. Autor UNIFESP Google Scholar
Castro, Ana P. M. Google Scholar
Yang, Ariana C. Google Scholar
Pastorino, Antonio C. Google Scholar
Sarinho, Emanuel S. Google Scholar
Institution Univ Fed Parana
Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Universidade Federal de Pernambuco (UFPE)
Abstract The subspecialty of pediatric allergy and immunology in Brazil is in its early years and progressing steadily. This review highlights the research developed in the past years aiming to show the characteristics of allergic and immunologic diseases in this vast country. Epidemiologic studies demonstrated the high prevalence of asthma in infants, children, and adolescents. Mortality rates and average annual variation of asthma hospitalization have reduced in all pediatric age groups. Indoor aeroallergen exposure is excessively high and contributes to the high rates of allergy sensitization. Prevalence of food allergy has increased to epidemic levels. Foods (35%), insect stings (30%), and drugs (23%) are the main etiological agents of anaphylaxis in children and adolescents. Molecular diagnosis of primary immunodeficiencies (PID) showed a high incidence of fungal infections including paracoccidioidomycosis in X-linked hyper-IgM syndrome, and the occurrence of BCG adverse reactions or other mycobacterial infections in patients with chronic granulomatous disease. Education in pediatric allergy and immunology is deficient for medical students, but residency programs are effective in training internists and pediatricians for the practice of allergy. the field of PID requires further training. Last, this review is a tribute to Prof. Dr. Charles Naspitz, one of the pioneers of our specialty in Brazil.
Keywords allergy
anaphylaxis
epidemiology
food allergy
immunodeficiencies
IgE sensitization
Language English
Date 2013-06-01
Published in Pediatric Allergy and Immunology. Hoboken: Wiley-Blackwell, v. 24, n. 4, p. 402-409, 2013.
ISSN 0905-6157 (Sherpa/Romeo, impact factor)
Publisher Wiley-Blackwell
Extent 402-409
Origin http://dx.doi.org/10.1111/pai.12069
Access rights Closed access
Type Review
Web of Science ID WOS:000319290700015
URI http://repositorio.unifesp.br/handle/11600/36416

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