HOW TO CHOOSE the IDEAL RENAL REPLACEMENT THERAPY in SEPSIS?

HOW TO CHOOSE the IDEAL RENAL REPLACEMENT THERAPY in SEPSIS?

Autor Filiponi, Thiago Corsi Autor UNIFESP Google Scholar
Durao, Marcelino de Souza Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Hosp Israelita Albert Einstein
Resumo Sepsis is the main cause of acute kidney injury (AKI) among individuals hospitalized in intensive care units. Acute kidney injury is an independent risk factor for mortality, and its occurrence increases the complexity and cost of treatment. However, the pathophysiological mechanisms of AKI remain unclear. Hemodynamic, vascular, tubular, cellular, inflammatory, and oxidative processes are involved. Individuals with AKI generally have various comorbidities and are elderly and hypercatabolic and on vasopressors and mechanical ventilation. Dialysis is the main treatment for AKI. Although there is no clear benefit of any specific dialysis modality, these patients are initially instructed to use continuous dialysis methods, especially for the most severe cases with multiple organ system dysfunctions and for those who display signs of hemodynamic instability. Recent studies demonstrate that patients should receive a dialysis dose of at least 25 mL.kg(-1).h(-1).
Palavra-chave Sepsis
renal replacement therapy
dialysis
Idioma Inglês
Data de publicação 2013-05-01
Publicado em Shock. Philadelphia: Lippincott Williams & Wilkins, v. 39, n. 7, p. 50-53, 2013.
ISSN 1073-2322 (Sherpa/Romeo, fator de impacto)
Publicador Lippincott Williams & Wilkins
Extensão 50-53
Fonte http://dx.doi.org/10.1097/SHK.0b013e31828fafa6
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000330251000011
Endereço permanente http://repositorio.unifesp.br/handle/11600/36239

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