KLEBSIELLA PNEUMONIAE CARBAPENEMASE-PRODUCING KLEBSIELLA PNEUMONIAE in the INTENSIVE CARE UNIT: A REAL CHALLENGE TO PHYSICIANS, SCIENTIFIC COMMUNITY, and SOCIETY

KLEBSIELLA PNEUMONIAE CARBAPENEMASE-PRODUCING KLEBSIELLA PNEUMONIAE in the INTENSIVE CARE UNIT: A REAL CHALLENGE TO PHYSICIANS, SCIENTIFIC COMMUNITY, and SOCIETY

Autor Carvalhaes, Cecilia Godoy Autor UNIFESP Google Scholar
Cayô, Rodrigo Autor UNIFESP Google Scholar
Gales, Ana Cristina Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo The prevalence of multidrug-resistant pathogens, especially in intensive care units, has increased and represents a great concern for medical and scientific community. Infections caused by these pathogens are associated with increased costs, length of hospitalization, and morbidity/mortality rates. the last decade was marked by the spread of carbapenem resistance determinants especially in Enterobacteriaceae isolates. in this review, the Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae is used as an example to discuss the difficulties in dealing with multidrug-resistant pathogens in the intensive care unit setting and how they represent a challenge to the medical-scientific community and, ultimately, the whole society.
Palavra-chave MDR pathogens
KPC
antimicrobial resistance
fitness cost
mortality
Idioma Inglês
Data de publicação 2013-05-01
Publicado em Shock. Philadelphia: Lippincott Williams & Wilkins, v. 39, n. 7, p. 32-37, 2013.
ISSN 1073-2322 (Sherpa/Romeo, fator de impacto)
Publicador Lippincott Williams & Wilkins
Extensão 32-37
Fonte http://dx.doi.org/10.1097/SHK.0b013e31828faf1f
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000330251000008
Endereço permanente http://repositorio.unifesp.br/handle/11600/36238

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