Predictive Factors of Overall Well-Being Using the EORTC QLQ-C15-PAL Extracted from the EORTC QLQ-C30

Predictive Factors of Overall Well-Being Using the EORTC QLQ-C15-PAL Extracted from the EORTC QLQ-C30

Autor Lam, Kinsey Google Scholar
Zeng, Liang Google Scholar
Zhang, Liying Google Scholar
Tseng, Ling-Ming Google Scholar
Hou, Ming-Feng Google Scholar
Fairchild, Alysa Google Scholar
Vassiliou, Vassilios Google Scholar
Jesus-Garcia, Reynaldo Autor UNIFESP Google Scholar
El-Din, Mohamed A. Alm Google Scholar
Kumar, Aswin Google Scholar
Forges, Fabien Google Scholar
Chie, Wei-Chu Google Scholar
Sahgal, Arjun Google Scholar
Poon, Michael Google Scholar
Chow, Edward Google Scholar
Instituição Univ Toronto
Natl Yang Ming Univ
Kaohsiung Med Univ Hosp
Cross Canc Inst
Bank Cyprus Oncol Ctr
Universidade Federal de São Paulo (UNIFESP)
Tanta Univ Hosp
Reg Canc Ctr
St Etienne Univ Hosp
Natl Taiwan Univ
Resumo Objective: the European Organization of Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire - Core 15 Palliative (EORTC QLQ-C15-PAL) was developed to assess quality of life (QOL) for the palliative cancer population to decrease patient burden. the purpose of this study was to compare predictive factors for well-being in the QLQ-C15-PAL extracted from the EORTC Quality of Life Questionnaire - Core 30 (QLQ-C30) with the QLQ-C30 itself.Methods and Materials: Patients with advanced cancer referred for treatment of bone metastases completed the QLQ-C30. Fifteen items from the QLQ-C15-PAL were extracted from the QLQ-C30. Univariate and multivariate analyses were used to determine predictive factors of the global QOL/health score in both tools. in the multivariate analyses, a p value of < 0.003 indicated statistical significance.Results: Overall, predictive factors were similar when analyzing data from both tools. Predictive factors for the QLQ-C30 were role functioning (p < 0.0001), fatigue (p < 0.0001), nausea/vomiting (p < 0.0001), and financial problems (p < 0.0001) and factors for the extracted QLQ-C15-PAL were physical functioning (p < 0.0001) and fatigue (p < 0.0001).Conclusions: Extraction of the QLQ-C15-PAL items from the QLQ-C30 resulted in similar predictive QOL domains for all patient subgroups analyzed individually. the QLQ-C15-PAL is reflective of the QLQ-C30 domains and is recommended for future studies involving patients in a palliative setting, as this shorter questionnaire reduces patient burden and may increase accrual and compliance, while maintaining a similar breadth of coverage and achieving the same predictive ability.
Idioma Inglês
Data de publicação 2013-04-01
Publicado em Journal of Palliative Medicine. New Rochelle: Mary Ann Liebert Inc, v. 16, n. 4, p. 402-408, 2013.
ISSN 1096-6218 (Sherpa/Romeo, fator de impacto)
Publicador Mary Ann Liebert Inc
Extensão 402-408
Fonte http://dx.doi.org/10.1089/jpm.2012.0398
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000316857000016
Endereço permanente http://repositorio.unifesp.br/handle/11600/36176

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