RETINAL NEOVASCULARIZATION SECONDARY TO PROLIFERATIVE DIABETIC RETINOPATHY CHARACTERIZED BY SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY

RETINAL NEOVASCULARIZATION SECONDARY TO PROLIFERATIVE DIABETIC RETINOPATHY CHARACTERIZED BY SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY

Author Cho, Hyung Google Scholar
Alwassia, Ahmad A. Google Scholar
Regiatieri, Caio V. Autor UNIFESP Google Scholar
Zhang, Jason Y. Google Scholar
Baumal, Caroline Google Scholar
Waheed, Nadia Google Scholar
Duker, Jay S. Google Scholar
Institution Tufts Med Ctr
Universidade Federal de São Paulo (UNIFESP)
Abstract Purpose: the purpose of this study was to characterize diabetic retinal neovascularization (NV) and accompanying retinal and vitreal morphologic changes using high-resolution spectral domain optical coherence tomography.Methods: A cross-sectional retrospective analysis was performed on 16 eyes of 14 nonconsecutive subjects with proliferative diabetic retinopathy that were seen between August 2011 and December 2011 at the New England Eye Center, Boston, MA. Patients who had NV of the disk, NV elsewhere, and intraretinal microvascular abnormalities were scanned using optical coherence tomography directly over the region of the abnormal vessels.Results: Characteristic changes of the retinal vasculature, retina, and vitreous were seen in the 16 eyes with NV. This study describes optical coherence tomography characteristics of 1) NV of the disk, 2) NV elsewhere, 3) intraretinal microvascular abnormality, 4) NV causing traction without retinal detachment; and 5) NV causing traction with retinal detachment. the morphologic appearance of vitreous traction was found to be consistent with the previous histologic reports.Conclusion: It is possible to image diabetic NV using spectral domain optical coherence tomography and to visualize the spectrum of retinal, retinal vascular, and vitreal changes seen through these areas of abnormal retinal vasculature. RETINA 33:542-547, 2013
Keywords neovascularization of the retina
neovascularization of the disk
intraretinal microvascular abnormalities
diabetes mellitus
proliferative diabetic retinopathy
optical coherence tomography
Language English
Sponsor Research to Prevent Blindness
NIH
Air Force Office of Scientific Research
Massachusetts Lions Eye Research Fund
Carl Zeiss Meditech, Inc
Optovue, Inc
Topcon Medical Systems, Inc
Grant number NIH: RO1-EY11289-23
NIH: R01-EY13178-07
NIH: R01-EY013516-07
Air Force Office of Scientific Research: FA9550-07-1-0101
Air Force Office of Scientific Research: FA9550-07-1-0014
Date 2013-03-01
Published in Retina-the Journal of Retinal and Vitreous Diseases. Philadelphia: Lippincott Williams & Wilkins, v. 33, n. 3, p. 542-547, 2013.
ISSN 0275-004X (Sherpa/Romeo, impact factor)
Publisher Lippincott Williams & Wilkins
Extent 542-547
Origin http://dx.doi.org/10.1097/IAE.0b013e3182753b6f
Access rights Closed access
Type Article
Web of Science ID WOS:000315455200011
URI http://repositorio.unifesp.br/handle/11600/36051

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