Corpus callosotomy in a patient with startle epilepsy

Corpus callosotomy in a patient with startle epilepsy

Author Garofalo Gomez, Nicolas Google Scholar
Hamad, Ana Paula Autor UNIFESP Google Scholar
Marinho, Murilo Autor UNIFESP Google Scholar
Tavares, Igor Melo Autor UNIFESP Google Scholar
Carrete, Henrique Autor UNIFESP Google Scholar
Caboclo, Luis Otavio Autor UNIFESP Google Scholar
Yacubian, Elza Márcia Targas Autor UNIFESP Google Scholar
Centeno, Ricardo Autor UNIFESP Google Scholar
Institution Cuban Inst Neurol & Neurosurg
Universidade Federal de São Paulo (UNIFESP)
Abstract Startle epilepsy is a syndrome of reflex epilepsy in which the seizures are precipitated by a sudden and surprising, usually auditory, stimulus. We describe herein a girl who had been suffering with startle-induced seizures since 2 years of age. She had focal, tonic and tonic-clonic seizures, refractory to antiepileptic treatment. Daily tonic seizures led to very frequent falls and morbidity. Neurologically, she had no deficit. Interictal EEG showed slow waves and epileptiform discharges in central and fronto-central regions. Video-polygraphic recordings of seizures, triggered by stimuli, showed generalised symmetric tonic posturing with ictal EEG, characterised by an abrupt and diffuse electrodecremental pattern of fast activity, followed by alpha-theta rhythm superimposed by epileptic discharges predominantly over the vertex and anterior regions. Magnetic resonance imaging showed no abnormalities. Corpus callosotomy was performed when the patient was 17. Since surgery, the patient (one year follow-up) has remained seizure-free. Corpus callosotomy may be considered in patients with startle epilepsy and tonic seizures, in the absence of focal lesions amenable to surgery. [Published with video sequences]
Keywords callosotomy
startle epilepsy
reflex seizure
Language English
Sponsor ALADE (Academia Latino Americana de Epilepsia)
ILAE (International League Against Epilepsy)
Date 2013-03-01
Published in Epileptic Disorders. Montrouge: John Libbey Eurotext Ltd, v. 15, n. 1, p. 76-79, 2013.
ISSN 1294-9361 (Sherpa/Romeo, impact factor)
Publisher John Libbey Eurotext Ltd
Extent 76-79
Origin http://dx.doi.org/10.1684/epd.2013.0553
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000317594400012
URI http://repositorio.unifesp.br/handle/11600/36011

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