Institutional prevention policies and rates of Group B Streptococcus infection among HIV-infected pregnant women and their infants in Latin America

Institutional prevention policies and rates of Group B Streptococcus infection among HIV-infected pregnant women and their infants in Latin America

Author Joao, Esau Google Scholar
Gouvea, Maria I. Google Scholar
Freimanis-Hance, Laura Google Scholar
Cohen, Rachel A. Google Scholar
Read, Jennifer S. Google Scholar
Melo, Victor Google Scholar
Duarte, Geraldo Google Scholar
Ivalo, Silvina Google Scholar
Machado, Daisy M. Autor UNIFESP Google Scholar
Pilotto, Jose Google Scholar
Siberry, George K. Google Scholar
NISDI LILAC Protocol Google Scholar
Institution Hosp Fed Serv Estado Rio de Janeiro
Inst Pesquisa Clin Evandro Chagas IPEC FIOCRUZ
Westat Corp
Eunice Kennedy Shriver Natl Inst Child Hlth & Hum
Natl Vaccine Program Off
Universidade Federal de Minas Gerais (UFMG)
Universidade de São Paulo (USP)
Hosp Gen Agudos Jose Maria Ramos Mejia
Universidade Federal de São Paulo (UNIFESP)
Hosp Geral Nova Iguacu
Fiocruz MS
Abstract Objective: To describe Group B Streptococcus (GBS) prevention policies at 12 Latin American sites participating in the NICHD (Eunice Kennedy Shriver National Institute of Child Health and Human Development) International Site Development Initiative (NISDI) Longitudinal Study in Latin American Countries (LILAC) and to determine rates of rectovaginal colonization and GBS-related disease among HIV-infected pregnant women and their infants. Methods: Site surveys were used to assess prevention policies and practices administered cross-sectionally during 2010. Data collected in NISDI from 2008 to 2010 regarding HIV-infected pregnant women were used to determine rates of colonization and GBS-related disease. Results: of the 9 sites with a GBS prevention policy, 7 performed routine rectovaginal screening for GBS. of the 401 women included in the NISDI study, 56.9% were at sites that screened. the GBS colonization rate was 8.3% (19/228 women; 95% confidence interval [CI], 5.1%-12.7%). Disease related to GBS occurred in 0.5% of the participants (2/401 women; 95% CI, 0.1%-1.8%); however, no GBS-related disease was reported among the 398 infants (95% CI, 0.0%-0.9%). Conclusion: Improved efforts to implement prevention policies and continued surveillance for GBS are needed to understand the impact of GBS among HIV-infected pregnant women and their infants in Latin America. (c) 2012 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
Keywords Group B Streptococcus
Infection rates
Institutional policy
Maternal HIV
Pregnancy
Language English
Sponsor Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Grant number Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD): HHSN267200800001C
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD): N01-HD-8-0001
Date 2013-02-01
Published in International Journal of Gynecology & Obstetrics. Clare: Elsevier B.V., v. 120, n. 2, p. 144-147, 2013.
ISSN 0020-7292 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 144-147
Origin http://dx.doi.org/10.1016/j.ijgo.2012.08.017
Access rights Closed access
Type Article
Web of Science ID WOS:000314433400009
URI http://repositorio.unifesp.br/handle/11600/35935

Show full item record




File

File Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Search


Browse

Statistics

My Account