Chronic Exercise Promotes Alterations in the Neuroendocrine Profile of Elderly People

Chronic Exercise Promotes Alterations in the Neuroendocrine Profile of Elderly People

Author Alves, E. S. Google Scholar
Souza, H. S. Google Scholar
Rosa, J. P. P. Google Scholar
Lira, F. S. Autor UNIFESP Google Scholar
Pimentel, G. D. Google Scholar
Santos, R. V. T. Autor UNIFESP Google Scholar
Oyama, L. M. Autor UNIFESP Google Scholar
Damaso, A. R. Autor UNIFESP Google Scholar
Oller do Nascimento, C. M. Autor UNIFESP Google Scholar
Viana, V. A. R. Autor UNIFESP Google Scholar
Boscolo, R. A. Autor UNIFESP Google Scholar
Grassmann, V. Autor UNIFESP Google Scholar
Santana, M. G. Autor UNIFESP Google Scholar
Tufik, S. Autor UNIFESP Google Scholar
Mello, M. T. de Autor UNIFESP Google Scholar
Institution Ctr Estudo Psicobiol Exercicio
Universidade Federal de São Paulo (UNIFESP)
Univ Extremo Sul Catarinense
Universidade Estadual de Campinas (UNICAMP)
Universidade Federal de Goiás (UFG)
Abstract Aging and physical inactivity are 2 factors that favour the development of cardiovascular disease, metabolic syndrome, obesity, and diabetes. in contrast, adopting a habitual moderate exercise routine may be a nonpharmacological treatment alternative for neuroendocrine aging disorders. We aimed to assess the effects of moderate exercise training on the metabolic profiles of elderly people with sedentary lifestyles. Fourteen sedentary, healthy, elderly male volunteers participated in a moderate training regimen for 60 min/day, 3 days/week for 24 weeks at a work rate equivalent to their ventilatory aerobic threshold. the environment was maintained at a temperature of 23 +/- 2 degrees C, with a humidity of 60 +/- 5 %. Blood samples for analysis were collected at 3 intervals: at baseline (1 week before training began), and 3 and 6 months after training. the training promoted increased aerobic capacity (relative VO2, and time and velocity to VO(2)max; (p < 0.05)) and reduced serum alpha-MSH (p < 0.05) after 3 months of training when compared with the baseline data. in addition, serum thyroid hormone (T3 and T4) was reduced after 6 months of training compared with baseline levels. Our results demonstrate that a moderate exercise training protocol improves the metabolic profile of older people, and metabolic adaptation is dependent on time.
Keywords aerobic capacity
moderate training
Language English
Sponsor Associacao Fundo de Incentivo a Pesquisa (AFIP)
Centro de Estudos em Psicobiologia and Exercicio (CEPE)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Universidade Federal de São Paulo (UNIFESP)
Date 2012-12-01
Published in Hormone and Metabolic Research. Stuttgart: Georg Thieme Verlag Kg, v. 44, n. 13, p. 975-979, 2012.
ISSN 0018-5043 (Sherpa/Romeo, impact factor)
Publisher Georg Thieme Verlag Kg
Extent 975-979
Access rights Closed access
Type Article
Web of Science ID WOS:000312501800008

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