Cardiovascular Disease in Early Kidney Transplantation: Comparison Between Living and Deceased Donor Recipients

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dc.contributor.author Yazbek, D. C. [UNIFESP]
dc.contributor.author Carvalho, A. B. de [UNIFESP]
dc.contributor.author Barros, C. S. [UNIFESP]
dc.contributor.author Marcassi, A. P. [UNIFESP]
dc.contributor.author Pestana, J. O. M. [UNIFESP]
dc.contributor.author Fachini, F. C.
dc.contributor.author Cassiolato, J. L.
dc.contributor.author Canziani, M. E. F. [UNIFESP]
dc.date.accessioned 2016-01-24T14:28:06Z
dc.date.available 2016-01-24T14:28:06Z
dc.date.issued 2012-12-01
dc.identifier http://dx.doi.org/10.1016/j.transproceed.2012.03.061
dc.identifier.citation Transplantation Proceedings. New York: Elsevier B.V., v. 44, n. 10, p. 3001-3006, 2012.
dc.identifier.issn 0041-1345
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/35578
dc.description.abstract Background. Cardiovascular disease (CVD) mortality is extremely high among kidney transplant recipients (KTRs), particularly in the first months after transplantation. Few data are available comparing the cardiovascular profile between KTRs from living versus deceased donors.Objectives and methods. the aim of the present study was to evaluate the prevalence of CVD in the first 2 months following transplantation, among 120 KTRs of living versus deceased donor organs.Results. Left ventricular hypertrophy was observed in 65% of patients, coronary artery calcification in 30%, and cardiac arrhythmias in 46%. CVD was more prevalent among KTRs from deceased versus living donors: ventricular hypertrophy 87% versus 59% (P = .008); coronary artery calcification 42% versus 24% (P = .04); and cardiac arrhythmias 59% versus 39% (P = .06). Multiple logistic regression analysis adjusted for age and dialysis vintage, showed graft donor to not be associated with the prevalence of any CVD (beta coefficient 0.912, 95% confidence interval 0.276-3.012, P = .88).Conclusion. in conclusion, the present study demonstrated an elevated prevalence of CVD among KTRs. Patient characteristics, mainly longer length on dialysis seemed to contribute to a greater prevalence of cardiovascular complications among KTRs from deceased compared with living donors on univariate but not multivariate analysis. en
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent 3001-3006
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof Transplantation Proceedings
dc.rights Acesso restrito
dc.title Cardiovascular Disease in Early Kidney Transplantation: Comparison Between Living and Deceased Donor Recipients en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Cardios Res Inst
dc.contributor.institution CDB
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Cardios Res Inst, São Paulo, Brazil
dc.description.affiliation CDB, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Div Nephrol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Div Nephrol, São Paulo, Brazil
dc.description.sponsorshipID FAPESP: 08/01420-5
dc.identifier.doi 10.1016/j.transproceed.2012.03.061
dc.description.source Web of Science
dc.identifier.wos WOS:000312042400022



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