Treatment for tobacco smoking: A new alternative?

Show simple item record Zaparoli, Jucara Xavier [UNIFESP] Fernandes Galduroz, Jose Carlos [UNIFESP] 2016-01-24T14:28:06Z 2016-01-24T14:28:06Z 2012-12-01
dc.identifier.citation Medical Hypotheses. Edinburgh: Churchill Livingstone, v. 79, n. 6, p. 867-868, 2012.
dc.identifier.issn 0306-9877
dc.description.abstract Smoking is a very common addiction and is associated with several kinds of diseases including different forms of cancer. Nicotine is the only substance present in cigarettes that can cause dependence. There are pharmacological treatments available to smoking cessation, but all of them are associated with side effects and low efficacy. Therefore, the development of new strategies and treatments is necessary. A possibility is the supplementation with polyunsaturated fatty acids (PUFAs) of the omega 3 series. It is known that low concentration of omega 3 can affect the dopaminergic neurotransmission, resulting in hypofunctioning of the mesocortical system. This system controls the mesolimbic system, associated in rewarding and dependence mechanisms. New perspectives of treatment focus on the reestablishment of the omega 3 levels, having as a result the normalization of the dopaminergic system and the reduction of the negative symptoms of withdrawal. (C) 2012 Elsevier B.V. All rights reserved. en
dc.format.extent 867-868
dc.language.iso eng
dc.publisher Churchill Livingstone
dc.relation.ispartof Medical Hypotheses
dc.rights Acesso restrito
dc.title Treatment for tobacco smoking: A new alternative? en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Universidade Federal de São Paulo, Dept Psychobiol, BR-04024002 São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Psychobiol, BR-04024002 São Paulo, Brazil
dc.identifier.doi 10.1016/j.mehy.2012.09.009
dc.description.source Web of Science
dc.identifier.wos WOS:000311773500035


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