Accuracy of anthropometric measurements in estimating fat mass in individuals with 21-hydroxylase deficiency

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dc.contributor.author Gonçalves, Ezequiel Moreira
dc.contributor.author Silva, Analiza Mónica
dc.contributor.author Santos, Diana A.
dc.contributor.author Lemos-Marini, Sofia Helena Valente de
dc.contributor.author Santos, Allan de Oliveira
dc.contributor.author Santos, Carolina Taddeo Mendes dos
dc.contributor.author Mello, Maricilda Palandi de [UNIFESP]
dc.contributor.author Guerra-Junior, Gil
dc.date.accessioned 2016-01-24T14:27:44Z
dc.date.available 2016-01-24T14:27:44Z
dc.date.issued 2012-10-01
dc.identifier http://dx.doi.org/10.1016/j.nut.2011.12.014
dc.identifier.citation Nutrition. New York: Elsevier B.V., v. 28, n. 10, p. 984-990, 2012.
dc.identifier.issn 0899-9007
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/35298
dc.description.abstract Objective: the use of anthropometric measurements to estimate the percentage of body fat (%BF) is easy and inexpensive. However, the accuracy of these methods in patients with 21-hydroxylase deficiency (21OHD) has not been explored. the objective of this study was to evaluate the accuracy of skinfold-based models, body mass index (BMI), and waist circumference (WC) in estimations of %BF using dual-energy X-ray absorptiometry (DXA) as the reference method in individuals with 21OHD.Methods: Fifty-four 21OHD patients (32 women and 22 men), aged 7 to 20 y, were recruited for the study. DXA was used to determine %BF; four predictive skinfold equations, BMI, and WC were assessed for accuracy in determining %BF.Results: All predictive skinfold equations were highly associated (R, range: 0.82-0.89) with DXA %BF values. in women, BMI and WC showed moderate correlations (R = 0.69 for both BMI and WC) with DXA values. in contrast, among men there was a low explanatory power for BMI (13%) and WC (4%) and high errors (BMI, 6.9%; WC, 7.4%). All predictive equations significantly underestimated %BF (range of differences, -4.1 to -8.9) compared with DXA (women, 31.3 +/- 6.1; men, 24.4 +/- 7.3), and large limits of agreement were observed (range, -15.3 to 1.7 and -15.5 to 4.2 for women and men, respectively).Conclusion: in children and adolescents with 21OHD, %BF as estimated by skinfold measurements was associated more strongly with DXA-assessed %BF than both BMI and WC. However, still, the skinfold-based assessment underestimated DXA %BF and showed moderate agreement (C) 2012 Elsevier Inc. All rights reserved. en
dc.description.sponsorship Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent 984-990
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof Nutrition
dc.rights Acesso aberto
dc.subject Anthropometry en
dc.subject DXA en
dc.subject Children en
dc.subject Adolescents en
dc.subject Congenital adrenal hyperplasia en
dc.title Accuracy of anthropometric measurements in estimating fat mass in individuals with 21-hydroxylase deficiency en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Universidade Estadual de Campinas (UNICAMP)
dc.contributor.institution Univ Tecn Lisboa
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Univ Estadual Campinas, UNICAMP, FCM, Growth & Body Composit Lab,Ctr Invest Pediat CIPE, Campinas, SP, Brazil
dc.description.affiliation Univ Estadual Campinas, FCM, Program Child & Adolescent Hlth, Campinas, SP, Brazil
dc.description.affiliation Univ Tecn Lisboa, Fac Human Kinet, Exercise & Hlth Lab, P-1100 Lisbon, Portugal
dc.description.affiliation Univ Estadual Campinas, FCM, Dept Pediat, Pediat Endocrinol Unit, Campinas, SP, Brazil
dc.description.affiliation Univ Estadual Campinas, Div Nucl Med, Campinas, SP, Brazil
dc.description.affiliation Univ Estadual Campinas, Mol Biol & Genet Engn Ctr, Campinas, SP, Brazil
dc.description.sponsorshipID CAPES: BEX 2018/10-1
dc.identifier.file WOS000309319600006.pdf
dc.identifier.doi 10.1016/j.nut.2011.12.014
dc.description.source Web of Science
dc.identifier.wos WOS:000309319600006



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