Tumor neuroectodérmico primitivo supratentorial: estudo de quatro casos

Tumor neuroectodérmico primitivo supratentorial: estudo de quatro casos

Alternative title Primitive neuroectodermal tumor of the central nervous system: report of four cases
Author Minett, Thaís Soares Cianciarullo Autor UNIFESP Google Scholar
Neves, Beatrice Maria J. Autor UNIFESP Google Scholar
Stávale, João Norberto Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract The clinicopathological and immunohistochemical features of four cases of primitive neuroectodermal tumors of the central nervous system were investigated. Three patients died. All cases showed vimentin-positive cells with the morphology of neoplastic cells and one case showed glial fibrillary acidic protein, neuron-specific enolase and neurofilament protein-positive cell. The present study indicates that this group of tumors have bad prognostics and may show immunocytochemical features indicating glial and/or neuronal differentiation.

As alterações clinicopatológicas e imuno-histoquímicas de quatro casos de tumores neuroectodérmicos primitivos do sistema nervoso central foram investigadas. Três pacientes morreram. Todos os casos mostraram células vimentina positivas com morfologia de células neoplásicas e um caso mostrou células neoplásicas com imunoexpressão para proteína glial fibrilar acídica, enolase neuro-específica e neurofilamento. O presente estudo indica que este grupo de tumores tem mau prognóstico e pode mostrar alterações imuno-histoquímicas que indicam diferenciação glial e/ou neuronal.
Keywords primitive neuroectodermal tumor
immunohistochemistry
differentiation
tumor neuroectodérmico primitivo
imuno-histoquímica
diferenciação
Language Portuguese
Date 1994-09-01
Published in Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 52, n. 3, p. 392-395, 1994.
ISSN 0004-282X (Sherpa/Romeo)
Publisher Academia Brasileira de Neurologia - ABNEURO
Extent 392-395
Origin http://dx.doi.org/10.1590/S0004-282X1994000300017
Access rights Open access Open Access
Type Article
SciELO ID S0004-282X1994000300017 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/352

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