Levels of selected persistent organic pollutants in blood from delivering women in seven selected areas of São Paulo State, Brazil

Levels of selected persistent organic pollutants in blood from delivering women in seven selected areas of São Paulo State, Brazil

Author Rudge, Cibele V. C. Google Scholar
Sandanger, Torkjel Google Scholar
Roellin, Halina B. Google Scholar
Calderon, Iracema M. P. Google Scholar
Volpato, Gustavo Google Scholar
Silva, Joao L. P. Google Scholar
Duarte, Geraldo Google Scholar
Neto, Corintio M. Google Scholar
Sass, Nelson Autor UNIFESP Google Scholar
Nakamura, Mary U. Autor UNIFESP Google Scholar
Odland, Jon O. Google Scholar
Rudge, Marilza V. C. Google Scholar
Institution Universidade de São Paulo (USP)
Univ Tromso
Norwegian Inst Air Res
S African MRC
Univ Pretoria
Universidade Estadual de Campinas (UNICAMP)
Hosp & Matern Leonor Mendes de Barros
Matern Vila Nova Cachoeirinha
Universidade Federal de São Paulo (UNIFESP)
Abstract Persistent organic pollutants (POPS) present in the living environment are thought to have detrimental health effects on the population, with pregnant women and the developing foetus being at highest risk. We report on the levels of selected POPs in maternal blood of 155 delivering women residing in seven regions within the São Paulo State, Brazil.The following selected POPs were measured in the maternal whole blood: 12 polychlorinated biphenyls (PCBs) congeners (IUPAC Nos. 99, 101, 118, 138, 153, 156, 163, 170, 180, 183, 187, 194); dichlordiphenyltrichloroethane p,p'-DDT, diphenyldichloroethylene p,p'-DDE and other pesticides such as hexachlorocyclohexanes (alpha-HCH, beta-HCH, gamma-HCH), hexachlorobenzene (HCB), chlordane derivatives cis-chlordane, trans-chlordane. oxy-chlordane, cis-nonachlor and trans-nonachlor.Statistical comparisons between regions were performed only on compounds having concentrations above LOD in 70% of the samples. PCB118 congener was found to be highest in the industrial site (mean 4.97 ng/g lipids); PCB138 congener concentration was highest in the Urban 3 site (mean 4.27 ng/g lipids) and congener PCB153 was highest in the industrial and Urban 3 sites with mean concentration of 7.2 ng/g lipids and 5.89 ng/g lipids respectively. Large differences in levels of p,p'-DDE between regions were observed with the Urban 3 and industrial sites having the highest concentrations of 645 ng/g lipids and 417 ng/g lipids, respectively; beta-HCH was found to be highest in the Rural 1 site; the gamma-HCH in Rural 1 and industrial; the HCB in the Rural 1 and industrial sites and oxy-chlordane and t-NC in the Rural 2 sites. An association between levels of some contaminants and maternal age and parity was also found. (C) 2011 Elsevier B.V. All rights reserved.
Keywords Pesticides exposure
Delivering women
Human blood
São Paulo State
Language English
Sponsor University of Tromso, Norway
University of Aarhus, Denmark
Arctic Monitoring and Assessment Programme (AMAP), Oslo, Norway
Nordic Council of Ministers, Copenhagen, Denmark
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Date 2012-04-01
Published in Environment International. Oxford: Pergamon-Elsevier B.V., v. 40, p. 162-169, 2012.
ISSN 0160-4120 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 162-169
Origin http://dx.doi.org/10.1016/j.envint.2011.07.006
Access rights Closed access
Type Article
Web of Science ID WOS:000301025600021
URI http://repositorio.unifesp.br/handle/11600/34757

Show full item record


File Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)




My Account