Ethnic disparity in spontaneous preterm birth and maternal pre-pregnancy body mass index

Ethnic disparity in spontaneous preterm birth and maternal pre-pregnancy body mass index

Autor Torloni, Maria Regina Autor UNIFESP Google Scholar
Fortunato, Stephen J. Google Scholar
Betran, Ana Pilar Google Scholar
Williams, Scott Google Scholar
Brou, Lina Google Scholar
Drobek, Cayce Owens Google Scholar
Merialdi, Mario Google Scholar
Menon, Ramkumar Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Centennial Womens Hosp
World Hlth Org
Vanderbilt Univ
Emory Univ
Univ Texas Med Branch Galveston
Resumo To investigate differences in pre-pregnancy BMI status in patients with spontaneous preterm birth (PTB) compared with term birth and assess the role of ethnicity as a risk modifier in BMI-associated PTB.A case-control study involving self-reported African American and Caucasian women delivering singletons in Nashville, TN, USA, 2003-2009. Maternal pre-pregnancy BMI was recorded in 447 PTB-cases (African American = 145, Caucasian = 302) and 1315 term-birth controls (African American = 522; Caucasian = 793). Crude and adjusted odds ratio (OR and AOR) for PTB were calculated using normal BMI (18.5-24.9 kg/m(2)) as reference. Age, education, marital status, income, smoking, parity, previous PTB and pregnancy weight gain were included as covariates in logistic regression.No significant differences were noted in the OR for PTB among different BMI categories when women of different ethnicity were combined. Odds of PTB were greater in obese than in normal weight Caucasian women, even after adjusting for confounders (AOR = 1.84, 95%CI [1.15, 2.95]). Obese African American women had a decreased crude OR for PTB, although this was not significant after adjusting for confounders (AOR = 0.72, 95%CI [0.38, 1.40]). the odds for early PTB (< 32 weeks) were decreased in obese compared with normal weight African American women (OR = 0.23, 95%CI [0.08, 0.70]), whereas they were increased in obese compared with normal weight Caucasian women (OR = 2.30, 95%CI [1.32, 4.00]).The risk for PTB in women with different pre-pregnancy BMI categories differs according to ethnicity.
Assunto Premature birth
Body mass index
Nutrition
Ethnic groups
African Americans
European continental ancestry group
Idioma Inglês
Financiador Thrasher Research Funds
Número do financiamento Thrasher Research Funds: 02818-3
Thrasher Research Funds: 21FY08-557
Data 2012-04-01
Publicado em Archives of Gynecology and Obstetrics. Heidelberg: Springer Heidelberg, v. 285, n. 4, p. 959-966, 2012.
ISSN 0932-0067 (Sherpa/Romeo, fator de impacto)
Editor Springer
Extensão 959-966
Fonte http://dx.doi.org/10.1007/s00404-011-2102-8
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000301543300011
URI http://repositorio.unifesp.br/handle/11600/34748

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