Analysis by MRI of Residual Tumor After Radiofrequency Ablation for Early Stage Breast Cancer

Analysis by MRI of Residual Tumor After Radiofrequency Ablation for Early Stage Breast Cancer

Author Vilar, Vanessa Sales Autor UNIFESP Google Scholar
Goldman, Suzan Menasce Autor UNIFESP Google Scholar
Ricci, Marcos Desiderio Google Scholar
Pincerato, Katia Google Scholar
Oliveira, Helio Google Scholar
Abud, Thiago Giansante Autor UNIFESP Google Scholar
Ajzen, Sergio Autor UNIFESP Google Scholar
Baracat, Edmund Chada Google Scholar
Szejnfeld, Jacob Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Abstract OBJECTIVE. the objective of our study was to evaluate the effectiveness of MRI in the detection of possible residual lesions after radiofrequency ablation (RFA) in the treatment of breast cancer.SUBJECTS and METHODS. We prospectively evaluated 14 patients who had undergone ultrasound-guided core biopsies diagnostic of invasive ductal carcinoma (IDC; range of diameters, 1.0-3.0 cm) and then ultrasound-guided percutaneous RFA with sentinel node biopsy as the primary treatment. Breast MRI was performed 1 week before RFA to evaluate tumor extension and again 3 weeks after RFA to verify the presence of possible residual lesions. Conventional surgical resection of the tumors was performed 1 week after RFA. the MRI findings were compared with histopathologic analyses to confirm the presence or absence of residual tumor.RESULTS. There was no residual enhancement in seven lesions on the postablation breast MRI scans. These findings were confirmed by negative histopathologic findings in the surgical specimens. the MRI scans of five patients showed small areas of irregular enhancement that corresponded to residual lesions. in the two remaining patients, we observed enhancement of almost the entire lesion, indicating that RFA had failed.CONCLUSION. Breast MRI is effective in detecting residual lesions after RFA in patients with IDC.
Keywords breast cancer
breast MRI
radiofrequency ablation
residual lesions
Language English
Date 2012-03-01
Published in American Journal of Roentgenology. Reston: Amer Roentgen Ray Soc, v. 198, n. 3, p. W285-W291, 2012.
ISSN 0361-803X (Sherpa/Romeo, impact factor)
Publisher Amer Roentgen Ray Soc
Extent W285-W291
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000301069000011

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