Esophageal diverticula and cancer

Show simple item record Herbella, F. A. M. [UNIFESP] Dubecz, A. Patti, M. G. 2016-01-24T14:17:53Z 2016-01-24T14:17:53Z 2012-02-01
dc.identifier.citation Diseases of the Esophagus. Malden: Wiley-Blackwell, v. 25, n. 2, p. 153-158, 2012.
dc.identifier.issn 1120-8694
dc.description.abstract Esophageal diverticula are rare. the association of cancer and diverticula has been described. Some authors adopt a conservative non-surgical approach in selected patients with diverticula whereas others treat the symptoms by diverticulopexy or myotomy only, leaving the diverticulum in situ. However, the risk of malignant degeneration should be may be taken in account if the diverticulum is not resected. the correct evaluation of the possible risk factors for malignancy may help in the decision making process. We performed a literature review of esophageal diverticula and cancer. the incidence of cancer in a diverticulum is 0.37, 1.8, and 0.6% for pharyngoesophageal, midesophageal, and epiphrenic diverticula, respectively. Symptoms may mimic those of the diverticulum or underlying motor disorder. Progressive dysphagia, unintentional weight loss, the presence of blood in the regurgitated material, regurgitation of peaces of the tumor, odynophagia, melena, hemathemesis, and hemoptysis are key symptoms. Risk factors for malignancy are old age, male gender, long-standing history, and larger diverticula. A carcinoma may develop in treated diverticula, even after resection. Outcomes are usually quoted as dismal because of a delayed diagnosis but several cases of superficial carcinoma have been described. the treatment follows the same principals as the therapy for esophageal cancer; however, diverticulectomy is enough in cases of superficial carcinomas. Patients must be carefully evaluated before therapy and a long-term follow-up is advisable. en
dc.format.extent 153-158
dc.language.iso eng
dc.publisher Wiley-Blackwell
dc.relation.ispartof Diseases of the Esophagus
dc.rights Acesso restrito
dc.subject epiphrenic diverticulum en
dc.subject esophageal cancer en
dc.subject esophageal diverticulum en
dc.subject esophagus en
dc.subject zenker diverticulum en
dc.title Esophageal diverticula and cancer en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Klinikum Nuernberg Nord
dc.contributor.institution Univ Chicago
dc.description.affiliation Universidade Federal de São Paulo, Escola Paulista Med, Dept Surg, São Paulo, Brazil
dc.description.affiliation Klinikum Nuernberg Nord, Dept Gen & Thorac Surg, Nurnberg, Germany
dc.description.affiliation Univ Chicago, Pritzker Sch Med, Dept Surg, Chicago, IL 60637 USA
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Escola Paulista Med, Dept Surg, São Paulo, Brazil
dc.identifier.doi 10.1111/j.1442-2050.2011.01226.x
dc.description.source Web of Science
dc.identifier.wos WOS:000300693000009


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