Airflow Obstruction in Never Smokers in Five Latin American Cities: the PLATINO Study

Airflow Obstruction in Never Smokers in Five Latin American Cities: the PLATINO Study

Author Perez-Padilla, Rogelio Google Scholar
Fernandez, Rosario Google Scholar
Lopez Varela, Maria Victorina Google Scholar
Montes de Oca, Maria Google Scholar
Muino, Adriana Google Scholar
Talamo, Carlos Google Scholar
Brito Jardim, Jose Roberto Autor UNIFESP Google Scholar
Valdivia, Gonzalo Google Scholar
Baptista Menezes, Ana Maria Google Scholar
Institution Inst Nacl Enfermedades Resp
Univ Republica
Cent Univ Venezuela
Universidade Federal de São Paulo (UNIFESP)
Pontificia Univ Catolica Chile
Abstract Background. Although chronic obstructive pulmonary disease (COPD) is mostly related to tobacco smoking, a variable proportion of COPD occurs in never smokers. We investigated differences between COPD in never smokers compared with smokers and subjects without COPD.Methods. PLATINO is a cross-sectional population-based study of five Latin American cities. COPD was defined as postbronchodilator FEV1/FVC <0.70 and FEV1 <80% of predicted values.Results. Among 5,315 subjects studied, 2278 were never smokers and 3036 were ever smokers. COPD was observed in 3.5% of never smokers and in 7.5% of ever smokers. Never smokers with COPD were most likely older and reported a medical diagnosis of asthma or previous tuberculosis. Underdiagnosis was as common in obstructed patients who never smoked as in ever smokers.Conclusions. Never smokers comprised 26% of all individuals with airflow obstruction. Obstruction was associated with female gender, older age and a diagnosis of asthma or tuberculosis. (C) 2012 IMSS. Published by Elsevier Inc.
Keywords Chronic pulmonary disease
Never smokers
Health status
Tobacco smoking
Language English
Sponsor Asociacion Latinoamericana de Torax (ALAT)
Date 2012-02-01
Published in Archives of Medical Research. New York: Elsevier B.V., v. 43, n. 2, p. 159-165, 2012.
ISSN 0188-4409 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 159-165
Access rights Closed access
Type Article
Web of Science ID WOS:000304507800010

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