Human papillomavirus infection in Brazilian women with normal cervical cytology

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dc.contributor.author Miranda, Priscila Mayrink [UNIFESP]
dc.contributor.author Pitol, Bruna Caroline Vieira
dc.contributor.author Moran, Mariana Soares
dc.contributor.author Silva, Nayara Nascimento Toledo
dc.contributor.author Felix, Priscila Mueller
dc.contributor.author Lima-Filho, Jose Luis
dc.contributor.author Carneiro, Claudia Martins
dc.contributor.author Silva, Ismael Dale Cotrim Guerreiro da [UNIFESP]
dc.contributor.author Carvalho, Rodrigo Franco
dc.contributor.author Lima, Angelica Alves
dc.contributor.author Beçak, Willy
dc.contributor.author Stocco, Rita de Cassia [UNIFESP]
dc.date.accessioned 2016-01-24T14:17:39Z
dc.date.available 2016-01-24T14:17:39Z
dc.date.issued 2012-01-01
dc.identifier http://dx.doi.org/10.4238/2012.June.29.8
dc.identifier.citation Genetics and Molecular Research. Ribeirao Preto: Funpec-editora, v. 11, n. 2, p. 1752-1761, 2012.
dc.identifier.issn 1676-5680
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/34406
dc.description.abstract We examined the prevalence of human papillomavirus (HPV) infection in a sample of Brazilian women presenting normal cervical cytology. Possible interactions between patient characteristics and HPV infection were analyzed in order to provide background data to improve cervical cancer screening and prophylaxis. Cervical samples of 399 women, received for routine evaluation in the Health Department of Ouro Preto, MG, Brazil, were subjected to HPV-DNA testing by PCR with MY09/11 primers. HPV-positive specimens were typed by RFLP. A structured epidemiological questionnaire was administered to each woman. HPV prevalence among these cytologically normal women was 11%. Twelve viral types were detected, the most common being HPV-16, -6, -61, -83, and -66. HPV was more prevalent in younger women; high-risk viral types were detected in 61% of the infected women and 27% of the infected women had multiple HPV infections. Significant associations of HPV infection were found with age, literacy, residence, marital status, lifetime number of sexual partners, and parity. We detected a great diversity of HPV types in women with normal cytology. This kind of information about local populations is useful for HPV prevention and vaccination strategies. en
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorship Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorship FACEPE (PRONEX)
dc.format.extent 1752-1761
dc.language.iso eng
dc.publisher Funpec-editora
dc.relation.ispartof Genetics and Molecular Research
dc.rights Acesso aberto
dc.subject HPV en
dc.subject Human papillomavirus en
dc.subject Cervical cancer screening en
dc.subject Normal cytology en
dc.subject Epidemiology en
dc.subject Risk factors en
dc.title Human papillomavirus infection in Brazilian women with normal cervical cytology en
dc.type Artigo
dc.contributor.institution Inst Butantan
dc.contributor.institution Univ Fed Ouro Preto
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Universidade Federal de Pernambuco (UFPE)
dc.contributor.institution Univ Fed Integracao Latinoamer
dc.description.affiliation Inst Butantan, Dept Genet, Genet Lab, São Paulo, Brazil
dc.description.affiliation Univ Fed Ouro Preto, Escola Farm, Dept Anal Clin, Ouro Preto, MG, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Ginecol, Lab Tocoginecol, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Morfol & Genet, São Paulo, Brazil
dc.description.affiliation Univ Fed Pernambuco, Dept Bioquim, Lab Imunopatol Keizo Asami, Recife, PE, Brazil
dc.description.affiliation Univ Fed Integracao Latinoamer, Dept Ciencias Biol, Foz Do Iguacu, PR, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Ginecol, Lab Tocoginecol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Morfol & Genet, São Paulo, Brazil
dc.identifier.doi 10.4238/2012.June.29.8
dc.description.source Web of Science
dc.identifier.wos WOS:000308633900009



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