Nepeta cataria L. var. citriodora (Becker) increases penile erection in rats

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dc.contributor.author Bernardi, Maria Martha
dc.contributor.author Kirsten, Thiago Berti
dc.contributor.author Lago, Joao Henrique Ghilardi [UNIFESP]
dc.contributor.author Giovani, Tatiane Marisis
dc.contributor.author Massoco, Cristina de Oliveira
dc.date.accessioned 2016-01-24T14:17:19Z
dc.date.available 2016-01-24T14:17:19Z
dc.date.issued 2011-10-11
dc.identifier http://dx.doi.org/10.1016/j.jep.2011.07.061
dc.identifier.citation Journal of Ethnopharmacology. Clare: Elsevier B.V., v. 137, n. 3, p. 1318-1322, 2011.
dc.identifier.issn 0378-8741
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/34143
dc.description.abstract Ethnopharmacological relevance: Nepeta cataria (NC), catnip, induces pleasure in cats and humans. Aim of the study: Because sexual behavior is involved in pleasure, the effect of NC on sexual behavior and penile erection was evaluated in male rats that were acutely fed chow enriched with 10% NC leaves. Further, yawning was monitored because we previously demonstrated that NC modifies dopaminergic-related behaviors and that sexual behavior is closely linked with the dopaminergic system. the general activity and the motor coordination were examined to investigate the possible motor and emotional interferences of the sexual performance.Material and methods: Male rats of the NC group received for a 4 h period the chow enriched with 10% NC leaves while the control groups received regular chow. Fifteen min after the end of the 4 h period of NC feeding the sexual behavior, apomorphine-induced penile erection and motor coordination were observed; the general activity in the open field was assessed 0, 15, 30 and 60 min after treatment.Results: NC treatment increased male rat's penile erection. A slightly facilitation on male rat sexual behavior and a decreased in general activity of NC treated rats were observed. No effects on motor coordination and yawning episodes were detected by the NC treatment.Conclusions: It was suggested that NC increases penile erection and slightly improves male rat sexual behavior by an action on dopaminergic systems. (C) 2011 Elsevier Ireland Ltd. All rights reserved. en
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorship Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.format.extent 1318-1322
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof Journal of Ethnopharmacology
dc.rights Acesso aberto
dc.subject Catnip en
dc.subject Penile erection en
dc.subject Sexual behavior en
dc.subject Sexual motivation en
dc.subject Motor coordination en
dc.subject Open field en
dc.subject Yawning en
dc.title Nepeta cataria L. var. citriodora (Becker) increases penile erection in rats en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Universidade de São Paulo (USP)
dc.contributor.institution Univ Paulista
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Univ São Paulo, Sch Vet Med, Dept Pathol, BR-05508000 São Paulo, Brazil
dc.description.affiliation Univ Paulista, Hlth Sci Inst, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Ciencias Exatas & Terra, Diadema, SP, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Ciencias Exatas & Terra, Diadema, SP, Brazil
dc.description.sponsorshipID CNPq: 301739/2007-2
dc.identifier.file WOS000297387000037.pdf
dc.identifier.doi 10.1016/j.jep.2011.07.061
dc.description.source Web of Science
dc.identifier.wos WOS:000297387000037



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