Sensitivity to aversive stimulation, posttraumatic symptoms and migraines: What do they have in common?

Sensitivity to aversive stimulation, posttraumatic symptoms and migraines: What do they have in common?

Author Corchs, Felipe Google Scholar
Mercante, Juliane P. Google Scholar
Guendler, Vera Z. Google Scholar
Masruha, Marcelo R. Autor UNIFESP Google Scholar
Vieira, Domingos Savio Autor UNIFESP Google Scholar
Bernik, Marcio A. Google Scholar
Zukerman, Eliova Google Scholar
Peres, Julio F. P. Google Scholar
Peres, Mario F. P. Autor UNIFESP Google Scholar
Institution Universidade de São Paulo (USP)
Hosp Israelita Albert Einstein
Universidade Federal de São Paulo (UNIFESP)
Abstract Studies have suggested that the high comorbidity observed between chronic migraine and anxiety disorders can be mediated through a third factor namely increased sensitivity to aversive stimulation. This trait may predispose for both chronic migraines, through medication overuse as an avoidance response, and anxiety disorders. Additional studies have shown that hyper sensitivity to aversive stimulation, migraine chronification and anxiety disorders share other characteristics such as serotonergic mediation and personality traits. Preliminary analysis of empirical data comparing the frequency the impact of traumatic events over chronic [EM] and episodic migraine [EM] patients gives further support to this hypothesis. in spite of CM and EM did not differ in terms of the occurrence of traumatic events, CM patients that had experienced at least one traumatic event during their lives had higher scores in re-experiencing and avoidance (but not in hyperarousal) symptoms than CM patients. These observations suggest that traumatic events have greater impact over CM than over EM patients. (C) 2011 Elsevier B.V. All rights reserved.
Language English
Date 2011-10-01
Published in Medical Hypotheses. Edinburgh: Churchill Livingstone, v. 77, n. 4, p. 534-535, 2011.
ISSN 0306-9877 (Sherpa/Romeo, impact factor)
Publisher Churchill Livingstone
Extent 534-535
Access rights Closed access
Type Article
Web of Science ID WOS:000295440300012

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