Increased basal plasma brain-derived neurotrophic factor levels in sprint runners

Increased basal plasma brain-derived neurotrophic factor levels in sprint runners

Author Correia, Paulo Roberto Autor UNIFESP Google Scholar
Scorza, Fulvio Alexandre Autor UNIFESP Google Scholar
Silva, Sergio Gomes da Autor UNIFESP Google Scholar
Pansani, Aline Autor UNIFESP Google Scholar
Toscano-Silva, Michelle Autor UNIFESP Google Scholar
Almeida, Antonio Carlos de Google Scholar
Arida, Ricardo Mario Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Univ Fed Sao Joao del Rei
Abstract Objective Exercise is known to enhance circulating brain-derived neurotrophic factor (BDNF) levels in healthy humans. BDNF changes have been measured in endurance but not in strength exercise. the present study aimed to investigate whether anaerobic activity such as sprinting differentially alters basal plasma BDNF concentration. Methods Brazilian sprinters (100 m) at either the international (Olympics and Outdoor World Championships) (n = 14) or the domestic level (n = 8), and sedentary subjects (n = 15), were recruited. Plasma BDNF concentrations were analyzed by enzyme-linked immunosorbent assay. Results the basal plasma BDNF concentrations were significantly higher in the international and the domestic sprinters than in the sedentary subjects. in addition, sprinters at the international level had higher plasma BDNF concentrations than those at the domestic level. Conclusion Our findings suggest that increased basal plasma BDNF level is related to enhanced exercise performance.
Keywords brain-derived neurotrophic factor
physical exercise
sprint
plasma
brain
human
Language English
Sponsor Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Instituto Nacional de Neurociencia Translacional (INNT)
Cooperacao Interinstitucional de Apoio a Pesquisas sobre o Cerebro (CInAPCe), Brazil
Date 2011-10-01
Published in Neuroscience Bulletin. New York: Springer, v. 27, n. 5, p. 325-329, 2011.
ISSN 1673-7067 (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 325-329
Origin http://dx.doi.org/10.1007/s12264-011-1531-5
Access rights Closed access
Type Article
Web of Science ID WOS:000295729500005
URI http://repositorio.unifesp.br/handle/11600/34099

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