Fetal hydrocephalus

Author Cavalheiro, Sergio Autor UNIFESP Google Scholar
Moron, Antonio Fernandes Autor UNIFESP Google Scholar
Almodin, Carlos Gilberto Autor UNIFESP Google Scholar
Suriano, Italo Capraro Autor UNIFESP Google Scholar
Hisaba, Vagner Autor UNIFESP Google Scholar
Dastoli, Patricia Autor UNIFESP Google Scholar
Barbosa, Mauricio Mendes Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Introduction Hydrocephalus is the most frequent and devastating illness affecting a fetus. the development of both ultrasonography and magnetic resonance, associated with laboratorial tests, has greatly facilitated its diagnosis.Materials and methods in the Fetal Medicine Service of the Federal University of São Paulo and in the Santa Joana/Pro-Matre Paulista Hospital Complex, in São Paulo, SP, Brazil, repeated cephalocenteses, ventricular-amniotic shunting, and neuroendoscopy were used to treat 57 fetuses with hydrocephalus, all of them at a gestational age under 32 weeks. Another eight fetuses had myelomeningocele and underwent correctional open surgery to prevent hydrocephalus.Results Thirty-nine patients were followed up for a period longer than 3 years and had their intelligence coefficient assessed: 26 of them were considered normal (IQ above 70); six had mild or moderate handicaps (IQ from 35 to 70), and seven were severely handicapped (IQ below 35). Out of the eight patients operated for correction of myelomeningocele, only two came to require shunting. There were no cases of maternal morbidity, and no infectious condition was observed in any of the patients subjected to intrauterine treatment.Conclusion Selected cases of isolated, evolutive, non-destructive hydrocephaly diagnosed before 32 gestational weeks may benefit from fetal neurosurgical procedures. With the accuracy improvement of diagnoses, the number of patients fitting into that group has become very small.
Keywords Fetal hydrocephalus
Cephalocentesis
Ventriculo-amniotic shunting
Neuroendoscopy
Myelomeningocele
Viral infection
Language English
Date 2011-10-01
Published in Childs Nervous System. New York: Springer, v. 27, n. 10, p. 1575-1583, 2011.
ISSN 0256-7040 (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 1575-1583
Origin http://dx.doi.org/10.1007/s00381-011-1539-1
Access rights Closed access
Type Article
Web of Science ID WOS:000295848500009
URI http://repositorio.unifesp.br/handle/11600/34092

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