Optical Coherence Tomography Enhanced Depth Imaging of Choroidal Tumors

Optical Coherence Tomography Enhanced Depth Imaging of Choroidal Tumors

Author Torres, Virginia L. L. Autor UNIFESP Google Scholar
Brugnoni, Nicole Google Scholar
Kaiser, Peter K. Google Scholar
Singh, Arun D. Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Cleveland Clin
Abstract PURPOSE: To describe the spectral-domain optical coherence tomography (SD-OCT) features of choroidal tumors imaged using enhanced depth imaging (EDI) technique.DESIGN: Prospective observational case series.METHODS: One tumor each from 23 eyes of 23 patients was included. All the patients underwent clinical fundus photography, ultrasonography, and EDI SD-OCT. Qualitative characteristics (tumor outline, reflectivity and/or shadowing of choroidal layers, and detection of inner sclera) and quantitative characteristics (measurement of maximum tumor thickness and the largest tumor diameter) were assessed.RESULTS: Patients (male = 12) were categorized as: amelanotic choroidal nevus (4), melanotic choroidal nevus (9), choroidal melanoma (3), circumscribed choroidal hemangioma (3), and choroidal metastasis (4). in all cases, EDI SD-OCT was able to identify the tumor distinctly from the surrounding normal choroid. Qualitative analysis revealed: amelanotic nevi, homogenous and medium reflective band with visible choroidal vessels; melanotic nevi and choroidal melanomas, high reflective band in the anterior choroid with shadowing, and nonvisualization of choroidal vessels and inner sclera; choroidal hemangiomas, medium/low reflective band without shadowing; and choroidal metastasis, low reflective band in the deep choroid with enlargement of the suprachoroidal space. Maximum tumor diameter and thickness was measurable by EDT SD-OCT only in 10 cases that were <9.0 mm in diameter and <1.0 mm in thickness (undetectable by ultrasonography).CONCLUSIONS: It is possible to obtain cross-sectional views of a variety of choroidal tumors using EDT SD-OCT. Small choroidal tumors nondetectable by ultrasonography can be objectively measured by this technique. (Am J Ophthalmol 2011;151:586-593. (C) 2011 by Elsevier Inc. All rights reserved.)
Language English
Date 2011-04-01
Published in American Journal of Ophthalmology. New York: Elsevier B.V., v. 151, n. 4, p. 586-593, 2011.
ISSN 0002-9394 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 586-593
Origin http://dx.doi.org/10.1016/j.ajo.2010.09.028
Access rights Closed access
Type Article
Web of Science ID WOS:000288974700006
URI http://repositorio.unifesp.br/handle/11600/33588

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