Spontaneous periodic hypothermia and hyperhidrosis: a possibly novel cerebral neurotransmitter disorder

Spontaneous periodic hypothermia and hyperhidrosis: a possibly novel cerebral neurotransmitter disorder

Author Masruha, Marcelo Rodrigues Autor UNIFESP Google Scholar
Lin, Jaime Autor UNIFESP Google Scholar
Arita, Juliana Harumi Autor UNIFESP Google Scholar
Castro Neto, Eduardo Ferreira de Autor UNIFESP Google Scholar
Scerni, Debora Amado Autor UNIFESP Google Scholar
Cavalheiro, Esper Abrão Autor UNIFESP Google Scholar
Naffah Mazzacoratti, Maria da Graca Autor UNIFESP Google Scholar
Vilanova, Luiz Celso Pereira Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Spontaneous periodic episodes of hypothermia still defy medical knowledge. in 1969, Shapiro et al. described the first two cases of spontaneous periodic hypothermia associated with agenesis of the corpus callosum. Recently, Dundar et al. reported a case of spontaneous periodic hypothermia and hyperhidrosis without corpus callosum agenesis, suggesting that the periodic episodes of hypothermia might be of epileptiform origin. Here we describe two paediatric patients with spontaneous periodic hypothermia without corpus callosum agenesis and demonstrate, to our knowledge for the first time, altered levels of neurotransmitter metabolites within the cerebro-spinal fluid.
Language English
Sponsor Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Date 2011-04-01
Published in Developmental Medicine and Child Neurology. Malden: Wiley-Blackwell, v. 53, n. 4, p. 378-380, 2011.
ISSN 0012-1622 (Sherpa/Romeo, impact factor)
Publisher Wiley-Blackwell
Extent 378-380
Origin http://dx.doi.org/10.1111/j.1469-8749.2010.03854.x
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000288380600021
URI http://repositorio.unifesp.br/handle/11600/33573

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