Frontal Assessment Battery (FAB) is a simple tool for detecting executive deficits in chronic cannabis users

Frontal Assessment Battery (FAB) is a simple tool for detecting executive deficits in chronic cannabis users

Author Fontes, Maria Alice Autor UNIFESP Google Scholar
Bolla, Karen I. Google Scholar
Cunha, Paulo Jannuzzi Google Scholar
Almeida, Priscila Previato Autor UNIFESP Google Scholar
Jungerman, Flavia Autor UNIFESP Google Scholar
Laranjeira, Ronaldo Ramos Autor UNIFESP Google Scholar
Bressan, Rodrigo A. Autor UNIFESP Google Scholar
Lacerda, Acioly L. T. Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Johns Hopkins Univ
Universidade de São Paulo (USP)
Inst Sinapse Neurociencias Clin
Ctr Pesquisa & Ensaios Clin Sinapse Bairral
Abstract Background: Cannabis is the most used illicit drug in the world, and its use has been associated with prefrontal cortex (PFC) dysfunction, including deficits in executive functions (EF). Considering that EF may influence treatment outcome, it would be interesting to have a brief neuropsychological battery to assess EF in chronic cannabis users (CCU). in the present study, the Frontal Assessment Battery (FAB), a brief, easy to use neuropsychological instrument aimed to evaluate EF, was used to evaluate cognitive functioning of CCU. Methods: We evaluated 107 abstinent CCU with the FAB and compared with 44 controls matched for age, estimated IQ, and years of education. Results: CCU performed poorly as compared to controls (FAB total score = 16.53 vs. 17.09, p .05). CCU had also a poor performance in the Motor Programming subtest (2.47 vs. 2.73, p .05). Conclusion: This study examined effects of cannabis in executive functioning and showed evidence that the FAB is sensitive to detect EF deficits in early abstinent chronic cannabis users. Clinical significance of these findings remains to be investigated in further longitudinal studies. FAB may be useful as a screening instrument to evaluate the necessity for a complete neuropsychological assessment in this population.
Keywords Prefrontal cortex
Executive cognitive functions
Language English
Date 2011-01-01
Published in Journal of Clinical and Experimental Neuropsychology. Philadelphia: Taylor & Francis Inc, v. 33, n. 5, p. 523-531, 2011.
ISSN 1380-3395 (Sherpa/Romeo, impact factor)
Publisher Taylor & Francis Inc
Extent 523-531
Access rights Closed access
Type Article
Web of Science ID WOS:000291279800003

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