Social play impairment following status epilepticus during early development

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dc.contributor.author Santos Castelhano, Adelisandra Silva
dc.contributor.author Scorza, Fulvio Alexandre [UNIFESP]
dc.contributor.author Triguero Veloz Teixeira, Maria Cristina
dc.contributor.author Arida, Ricardo Mario [UNIFESP]
dc.contributor.author Cavalheiro, Esper Abrao [UNIFESP]
dc.contributor.author Cysneiros, Roberta Monterazzo
dc.date.accessioned 2016-01-24T14:05:30Z
dc.date.available 2016-01-24T14:05:30Z
dc.date.issued 2010-10-01
dc.identifier http://dx.doi.org/10.1007/s00702-010-0460-1
dc.identifier.citation Journal of Neural Transmission. Wien: Springer Wien, v. 117, n. 10, p. 1155-1160, 2010.
dc.identifier.issn 0300-9564
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/32943
dc.description.abstract Neonatal status epilepticus (SE) disrupts prefrontal cortex and thalamus, brain regions related to social play. Juvenile play was evaluated using the intruder-resident paradigm following SE in 9-day-old Wistar pups of both genders. Quite interestingly, we demonstrated for the first time that neonatal SE produces social impairment in male rats, reduces locomotor activity in both genders and enhances self-grooming in female. Additional studies are necessary to clarify if these effects can impair social behavior across the life span. en
dc.description.sponsorship MACKPESQUISA
dc.description.sponsorship Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.format.extent 1155-1160
dc.language.iso eng
dc.publisher Springer
dc.relation.ispartof Journal of Neural Transmission
dc.rights Acesso restrito
dc.subject Gender en
dc.subject Neonatal en
dc.subject Social interaction en
dc.subject Status epilepticus en
dc.title Social play impairment following status epilepticus during early development en
dc.type Artigo
dc.rights.license http://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.contributor.institution Univ Presbiteriana Mackenzie
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Univ Presbiteriana Mackenzie, Neurobiol Lab, Programa Posgrad Disturbios Desenvolvimento, BR-01302907 São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Disciplina Neurol Expt, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Fisiol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Disciplina Neurol Expt, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Fisiol, São Paulo, Brazil
dc.identifier.doi 10.1007/s00702-010-0460-1
dc.description.source Web of Science
dc.identifier.wos WOS:000284782100004



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