MICROCIRCULATORY EVALUATION in SEPSIS: A DIFFICULT TASK

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dc.contributor.author Koh, Ivan H. J. [UNIFESP]
dc.contributor.author Díaz, José Luis Menchaca [UNIFESP]
dc.contributor.author Koh, Tarso H. [UNIFESP]
dc.contributor.author Souza, Ricardo L. [UNIFESP]
dc.contributor.author Shu, Christopher M. [UNIFESP]
dc.contributor.author Rogerio, Victor E. [UNIFESP]
dc.contributor.author Liberatore, Ana M. A. [UNIFESP]
dc.date.accessioned 2016-01-24T14:05:21Z
dc.date.available 2016-01-24T14:05:21Z
dc.date.issued 2010-09-01
dc.identifier http://dx.doi.org/10.1097/SHK.0b013e3181e7e80c
dc.identifier.citation Shock. Philadelphia: Lippincott Williams & Wilkins, v. 34, p. 27-33, 2010.
dc.identifier.issn 1073-2322
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/32841
dc.description.abstract Microcirculatory dysfunction plays a pivotal role in the pathogenesis of severe sepsis and septic shock; hence, microcirculation blood flow monitoring has gained increasing attention. However, microcirculatory imaging is still investigational in human sepsis and has not yet been incorporated into routine clinical practice for several reasons, including the difficult interpretation of microcirculation imaging data, difficulty to draw a parallel between sublingual microcirculation imaging and organ microcirculation dysfunction, as well as the absence of microvessel dysfunction parameters defining sequential microcirculatory changes from the early to late stages of the disease, which could aid in the context of therapeutic approaches and of prognostic parameters. the purpose of this review was to bridge the experimental abdominal organ microvascular derangement kinetics and clinical aspects of microcirculatory findings in the early phase of severe sepsis/septic shock. en
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorship Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.format.extent 27-33
dc.language.iso eng
dc.publisher Lippincott Williams & Wilkins
dc.relation.ispartof Shock
dc.rights Acesso aberto
dc.subject Microcirculation en
dc.subject severe sepsis en
dc.subject septic shock en
dc.subject intravital microscopy en
dc.subject sidestream dark-field imaging en
dc.subject orthogonal polarization spectral imaging en
dc.title MICROCIRCULATORY EVALUATION in SEPSIS: A DIFFICULT TASK en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Universidade Federal de São Paulo, Dept Surg, BR-04039032 São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Surg, BR-04039032 São Paulo, Brazil
dc.identifier.doi 10.1097/SHK.0b013e3181e7e80c
dc.description.source Web of Science
dc.identifier.wos WOS:000281038500005



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