Efficacy of cytology for the diagnosis of Chlamydia trachomatis in pregnant women

Efficacy of cytology for the diagnosis of Chlamydia trachomatis in pregnant women

Author Cornetta, Maria da Conceição de Mesquita Autor UNIFESP Google Scholar
Gonçalves, Ana Katherine da Silveira Google Scholar
Bertini, Anna Maria Autor UNIFESP Google Scholar
Institution Federal University of Rio Grande do Norte
Universidade Federal de São Paulo (UNIFESP)
Abstract This study evaluated the effectiveness of Papanicolaou staining for the initial diagnosis of Chlamydial infection in pregnant women. A hundred thirteen patients were examined with a Papanicolaou test, independent of gestational age, parity or maternal age. Three endocervical samples were collected; the first two were collected with a brush (Cytobrush plus, Mediscand, Sweden) and the third with Ayre's spatula. The first specimen was used for McCoy cell culture and the other two were examined cytologically. Chlamydial infection was detected in 9 (7.9%) patients. Only one (0.8%) was diagnosed by cytological exam. The sensitivity and specificity of the cytological examination were 10 and 98%, respectively. The estimated positive predictive value was 33.3% and the negative predictive value was 92.7%. When Papanicolaou stain diagnosis suggests Chlamydia, a more specific complementary exam should be added to confirm infection; subsequently adequate treatment can be implemented, thereby preventing the frequent complications of untreated subclinical infections.
Keywords Chlamydia trachomatis
pregnancy
infection
and cervical cytology
Language English
Date 2006-10-01
Published in Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 10, n. 5, p. 337-340, 2006.
ISSN 1413-8670 (Sherpa/Romeo)
Publisher Brazilian Society of Infectious Diseases
Extent 337-340
Origin http://dx.doi.org/10.1590/S1413-86702006000500007
Access rights Open access Open Access
Type Article
SciELO ID S1413-86702006000500007 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/3283

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