Regional Variation in Asthma Symptom Prevalence in Latin American Children

Regional Variation in Asthma Symptom Prevalence in Latin American Children

Autor Mallol, Javier Google Scholar
Sole, Dirceu Autor UNIFESP Google Scholar
Baeza-Bacab, Manuel Google Scholar
Aguirre-Camposano, Viviana Google Scholar
Soto-Quiros, Manuel Google Scholar
Baena-Cagnani, Carlos Google Scholar
Latin American Isaac Grp Google Scholar
Instituição USACH
Universidade Federal de São Paulo (UNIFESP)
Auton Univ Yucatan
Natl Childrens Hosp
Univ Cordoba
Univ Genoa
Resumo Objectives. This study investigates the distribution pattern of asthma symptom prevalence in Latin American children aged 13-14 years. Methods. A randomized, cross-sectional and multicentric study on the prevalence and severity of asthma symptoms (lifetime asthma, current wheezing, and frequent sleep disturbance by wheezing) was conducted in 165,917 schoolchildren from 56 centers in 17 Latin American countries, as part of the International Study of Asthma and Allergies in Childhood (ISAAC), Phase Three. Results. the prevalence of lifetime asthma prevalence ranged from 1.2% to 33.1%, whereas current wheezing went from 3.9% to 30.8% and frequent sleep disturbance from 0.6% to 6.1%. An important proportion of centers (55%) reported a prevalence of asthma symptoms over 15%. There was no significant correlation between asthma symptom prevalence and latitude, altitude, or tropical setting. At country level, the prevalence of asthma was not associated with gross national income (GNI), proportion of population under the poverty line, or ancestry. Conclusions. This study suggests that ecological interactions, probably typical for each locality, may be the main determinants for the large variability of asthma prevalence in Latin America. the high prevalence of asthma symptoms found in children living in areas with low socioeconomic development would challenge the protective role against asthma of factors related to low hygiene and poverty; contrarily, in this region they would act as risk factors.
Assunto asthma
Idioma Inglês
Data 2010-08-01
Publicado em Journal of Asthma. Philadelphia: Taylor & Francis Inc, v. 47, n. 6, p. 644-650, 2010.
ISSN 0277-0903 (Sherpa/Romeo, fator de impacto)
Editor Taylor & Francis Inc
Extensão 644-650
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000282518900009

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