EULAR/PRINTO/PRES criteria for Henoch-Schonlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria

EULAR/PRINTO/PRES criteria for Henoch-Schonlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria

Autor Ozen, Seza Google Scholar
Pistorio, Angela Google Scholar
Iusan, Silvia M. Google Scholar
Bakkaloglu, Aysin Google Scholar
Herlin, Troels Google Scholar
Brik, Riva Google Scholar
Buoncompagni, Antonella Google Scholar
Lazar, Calin Google Scholar
Bilge, Ilmay Google Scholar
Uziel, Yosef Google Scholar
Rigante, Donato Google Scholar
Cantarini, Luca Google Scholar
Hilario, Maria Odete Autor UNIFESP Google Scholar
Silva, Clovis A. Google Scholar
Alegria, Mauricio Google Scholar
Norambuena, Ximena Google Scholar
Belot, Alexandre Google Scholar
Berkun, Yackov Google Scholar
Estrella, Amparo Ibanez Google Scholar
Olivieri, Alma Nunzia Google Scholar
Alpigiani, Maria Giannina Google Scholar
Rumba, Ingrida Google Scholar
Sztajnbok, Flavio Google Scholar
Tambic-Bukovac, Lana Google Scholar
Breda, Luciana Google Scholar
Al-Mayouf, Sulaiman Google Scholar
Mihaylova, Dimitrina Google Scholar
Chasnyk, Vyacheslav Google Scholar
Sengler, Claudia Google Scholar
Klein-Gitelman, Maria Google Scholar
Djeddi, Djamal Google Scholar
Nuno, Laura Google Scholar
Pruunsild, Chris Google Scholar
Brunner, Jurgen Google Scholar
Kondi, Anuela Google Scholar
Pagava, Karaman Google Scholar
Pederzoli, Silvia Google Scholar
Martini, Alberto Google Scholar
Ruperto, Nicolino Google Scholar
PRINTO Google Scholar
Instituição Hacettepe Univ
IRCCS G Gaslini
PRINTO
Aarhus Univ Hosp
Rambam Med Ctr
Clin Pediat 1
Istanbul Univ
Meir Med Ctr
Univ Cattolica Sacro Cuore
Med Clin & Sci Immunol Ist
Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Hosp Ninos Benjamin Bloom
Hosp Dr Exequiel Gonzalez Cortes
Hop Femme Mere Enfant
Safra Childrens Hosp
Inst Salud Nino
Univ Naples 2
IRCCS Ist G Gaslini
Latvian State Univ
Hosp Univ Pedro Ernesto
Univ Zagreb
Univ G dAnnunzio
King Faisal Specialist Hosp & Res Ctr
Univ Children Hosp
Hosp Paediat Dept
Charite
Childrens Mem Hosp
Dept Pediat
Hosp Gen Univ La Paz
Tartu Univ Hosp
Med Univ
Tblisi State Med Univ
Univ Genoa
Resumo Objectives To validate the previously proposed classification criteria for Henoch-Schonlein purpura (HSP), childhood polyarteritis nodosa (c-PAN), c-Wegener granulomatosis (c-WG) and c-Takayasu arteritis (c-TA).Methods Step 1: retrospective/prospective webdata collection for children with HSP, c-PAN, c-WG and c-TA with age at diagnosis <= 18 years. Step 2: blinded classification by consensus panel of a representative sample of 280 cases. Step 3: statistical (sensitivity, specificity, area under the curve and.-agreement) and nominal group technique consensus evaluations.Results 827 patients with HSP, 150 with c-PAN, 60 with c-WG, 87 with c-TA and 52 with c-other were compared with each other. A patient was classified as HSP in the presence of purpura or petechiae (mandatory) with lower limb predominance plus one of four criteria: (1) abdominal pain; (2) histopathology (IgA); (3) arthritis or arthralgia; (4) renal involvement. Classification of c-PAN required a systemic inflammatory disease with evidence of necrotising vasculitis OR angiographic abnormalities of medium-/small-sized arteries (mandatory criterion) plus one of five criteria: (1) skin involvement; (2) myalgia/muscle tenderness; (3) hypertension; (4) peripheral neuropathy; (5) renal involvement. Classification of c-WG required three of six criteria: (1) histopathological evidence of granulomatous inflammation; (2) upper airway involvement; (3) laryngo-tracheo-bronchial involvement; (4) pulmonary involvement (x-ray/CT); (5) antineutrophilic cytoplasmic antibody positivity; (6) renal involvement. Classification of c-TA required typical angiographic abnormalities of the aorta or its main branches and pulmonary arteries (mandatory criterion) plus one of five criteria: (1) pulse deficit or claudication; (2) blood pressure discrepancy in any limb; (3) bruits; (4) hypertension; (5) elevated acute phase reactant.Conclusion European League Against Rheumatism/Paediatric Rheumatology International Trials Organisation/Paediatric Rheumatology European Society propose validated classification criteria for HSP, c-PAN, c-WG and c-TA with high sensitivity/specificity.
Idioma Inglês
Financiador EULAR/PRINTO/PRES
Data de publicação 2010-05-01
Publicado em Annals of the Rheumatic Diseases. London: B M J Publishing Group, v. 69, n. 5, p. 798-806, 2010.
ISSN 0003-4967 (Sherpa/Romeo, fator de impacto)
Publicador B M J Publishing Group
Extensão 798-806
Fonte http://dx.doi.org/10.1136/ard.2009.116657
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000276982300004
Endereço permanente http://repositorio.unifesp.br/handle/11600/32490

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