A survey on clinical presentation and nutritional status of infants with suspected cow' milk allergy

A survey on clinical presentation and nutritional status of infants with suspected cow' milk allergy

Autor Vieira, Mario C. Google Scholar
Morais, Mauro Batista de Autor UNIFESP Google Scholar
Spolidoro, Jose V. N. Google Scholar
Toporovski, Mauro S. Google Scholar
Cardoso, Ary L. Google Scholar
Araujo, Gabriela T. B. Google Scholar
Nudelman, Victor Autor UNIFESP Google Scholar
Fonseca, Marcelo Cunio Machado Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Hosp Pequeno Principe
Pontificia Univ Catolica
Universidade de São Paulo (USP)
Axia Bio Consulting
Hosp Albert Einstein
Resumo Background: Cow's milk is the most common food allergen in infants and the diagnosis of cow's milk allergy is difficult, even with the use of several diagnostic tests. Therefore, elimination diets and challenge tests are essential for the diagnosis and treatment of this disorder. the aim of this study is to report the clinical presentation and nutritional status of children evaluated by pediatric gastroenterologists for the assessment of symptoms suggestive of cow's milk allergy.Methods: An observational cross-sectional study was performed among 9,478 patients evaluated by 30 pediatric gastroenterologists for 40 days in 5 different geographical regions in Brazil. Clinical data were collected from patients with symptoms suggestive of cow's milk allergy. the nutritional status of infants (age <= 24 months) seen for the first time was evaluated according to z-scores for weight-for-age, weight-for-height, and height-for-age. Epi-Info (CDC-NCHS, 2000) software was used to calculate z-scores.Results: the prevalence of suspected cow's milk allergy in the study population was 5.4% (513/9,478), and the incidence was 2.2% (211/9,478). Among 159 infants seen at first evaluation, 15.1% presented with a low weight-for-age z score (< -2.0 standard deviation - SD), 8.7% with a low weight-for-height z score (< -2.0 SD), and 23.9% with a low height-for-age z score (< -2.0 SD).Conclusion: the high prevalence of nutritional deficits among infants with symptoms suggestive of cow's milk allergy indicates that effective elimination diets should be prescribed to control allergy symptoms and to prevent or treat malnutrition.
Idioma Inglês
Financiador Support Advanced Medical Nutrition Danone
Data de publicação 2010-04-23
Publicado em Bmc Pediatrics. London: Biomed Central Ltd, v. 10, 7 p., 2010.
ISSN 1471-2431 (Sherpa/Romeo, fator de impacto)
Publicador Biomed Central Ltd
Extensão 7
Fonte http://dx.doi.org/10.1186/1471-2431-10-25
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000278231100001
Endereço permanente http://repositorio.unifesp.br/handle/11600/32481

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