Subclinical hyperthyroidism and sudden unexpected death in epilepsy

Subclinical hyperthyroidism and sudden unexpected death in epilepsy

Autor Scorza, Fulvio A. Autor UNIFESP Google Scholar
Arida, Ricardo M. Autor UNIFESP Google Scholar
Cysneiros, Roberta M. Google Scholar
Terra, Vera C. Google Scholar
Albuquerque, Manly de Autor UNIFESP Google Scholar
Machado, Helio R. Google Scholar
Cavalheiro, Esper A. Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Univ Presbiteriana Mackenzie
Universidade de São Paulo (USP)
Resumo Epilepsy is the most common serious neurological condition and sudden unexpected death in epilepsy (SUDEP) is the most important direct epilepsy-related cause of death. Information concerning risk factors for SUDEP is conflicting, but high seizure frequency is a potential risk factor. Additionally, potential pathomechanisms for SUDEP are unknown, but it is very probable that cardiac arrhythmias during and between seizures or transmission of epileptic activity to the heart via the autonomic nervous system potentially play a role. in parallel, several studies have shown a link between hormones and epilepsy. However, exact knowledge regarding the association of thyroid hormones and epilepsy is lacking. As subclinical hyperthyroidism has been linked with increased risk of cardiovascular disease, we propose in this paper that SUDEP, at least in some cases, could be related with subclinical thyroid dysfunction. (C) 2009 Elsevier B.V. All rights reserved.
Idioma Inglês
Data de publicação 2010-04-01
Publicado em Medical Hypotheses. Edinburgh: Churchill Livingstone, v. 74, n. 4, p. 692-694, 2010.
ISSN 0306-9877 (Sherpa/Romeo, fator de impacto)
Publicador Churchill Livingstone
Extensão 692-694
Fonte http://dx.doi.org/10.1016/j.mehy.2009.10.045
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000276697800019
Endereço permanente http://repositorio.unifesp.br/handle/11600/32423

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