High-resolution computed tomography findings from adult patients with Influenza A (H1N1) virus-associated pneumonia

High-resolution computed tomography findings from adult patients with Influenza A (H1N1) virus-associated pneumonia

Autor Marchiori, Edson Google Scholar
Zanetti, Glaucia Google Scholar
Hochhegger, Bruno Google Scholar
Rodrigues, Rosana Souza Google Scholar
Pantaleao Fontes, Cristina Asvolinsque Google Scholar
Nobre, Luiz Felipe Google Scholar
Mancano, Alexandre Dias Google Scholar
Meirelles, Gustavo Autor UNIFESP Google Scholar
Irion, Klaus Loureiro Google Scholar
Instituição Universidade Federal Fluminense (UFF)
Universidade Federal do Rio de Janeiro (UFRJ)
Universidade Federal de Santa Catarina (UFSC)
Anchieta Hosp
Universidade Federal de São Paulo (UNIFESP)
Liverpool Heart & Chest Hosp NHS Trust
Royal Liverpool & Broadgreen Univ Hosp NHS
DOR Inst Res & Educ
Resumo Objective: the aim of this study was to assess the high-resolution computed tomography (HRCT) findings at presentation in patients diagnosed with Influenza A (H1N1) virus-associated pneumonia.Materials and methods: We reviewed the HRCT findings from 20 patients diagnosed with Influenza A (H1N1) and compared their HRCT scans with chest radiographs, obtained on the same day. the imaging studies were obtained 4-9 days after the onset of symptoms. the patients included 11 men and 9 women (ages 24-62 years; mean 42.7 years). All patients had a body temperature greater than 100.4 degrees F (> 38 degrees C), tachypnea, and cough. Other common symptoms included diarrhea (60%) and sore throat (30%). the radiographs and HRCT scans were reviewed independently by two observers who reached a consensus decision.Results: the predominant HRCT findings consisted of bilateral ground-glass opacities (n = 12), bilateral areas of consolidation (n = 2), or a mixed bilateral pattern of ground-glass opacities and areas of consolidation (n = 6). the abnormalities were bilateral in all of the 20 patients, had a predominantly sub-pleural distribution in 13 patients, and had a random distribution in the remaining 7 patients. the predominant radiographic findings were consolidations. Normal radiographs were found in 4 out of the 20 patients.Conclusion: HRCT may reveal parenchymal abnormalities in patients with Influenza A (H1N1) infection who have normal findings on radiographs. the predominant HRCT findings were bilateral, peripheral, ground-glass opacities and/or bilateral areas of consolidation. the patients who presented consolidations had more severe clinical course. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
Palavra-chave High-resolution computed tomography
Influenza A
H1N1 virus
Viral pneumonia
Idioma Inglês
Data de publicação 2010-04-01
Publicado em European Journal of Radiology. Clare: Elsevier B.V., v. 74, n. 1, p. 93-98, 2010.
ISSN 0720-048X (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 93-98
Fonte http://dx.doi.org/10.1016/j.ejrad.2009.11.005
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000277565200013
Endereço permanente http://repositorio.unifesp.br/handle/11600/32418

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