Treatment of Obese Adolescents: the Influence of Periodization Models and ACE Genotype

Treatment of Obese Adolescents: the Influence of Periodization Models and ACE Genotype

Autor Foschini, Denis Autor UNIFESP Google Scholar
Araújo, Ronaldo de Carvalho Autor UNIFESP Google Scholar
Bacurau, Reury Frank Pereira Google Scholar
Piano, Aline de Autor UNIFESP Google Scholar
De Almeida, Sandro S. Autor UNIFESP Google Scholar
Carnier, June Autor UNIFESP Google Scholar
Rosa, Thiago D. S. Autor UNIFESP Google Scholar
Mello, Marco Tulio de Autor UNIFESP Google Scholar
Tufik, Sergio Autor UNIFESP Google Scholar
Damaso, Ana R. Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Resumo The aims of the present study were to compare the effects of two periodization models on metabolic syndrome risk factors in obese adolescents and verify whether the angiotensin-converting enzyme (ACE) genotype is important in establishing these effects. A total of 32 postpuberty obese adolescents were submitted to aerobic training (AT) and resistance training (RT) for 14 weeks. the subjects were divided into linear periodization (LP, n = 16) or daily undulating periodization (DUP, n = 16). Body composition, visceral and subcutaneous fat, glycemia, insulinemia, homeostasis model assessment of insulin resistance (HOMA-IR), lipid profiles, blood pressure, maximal oxygen consumption (VO(2max)), resting metabolic rate (RMR), muscular endurance were analyzed at baseline and after intervention. Both groups demonstrated a significant reduction in body mass, BMI, body fat, visceral and subcutaneous fat, total and low-density lipoprotein cholesterol, blood pressure and an increase in fat-free mass, VO(2max), and muscular endurance. However, only DUP promoted a reduction in insulin concentrations and HOMA-IR. It is important to emphasize that there was no statics difference between LP and DUP groups; however, it appears that there may be bigger changes in the DUP than LP group in some of the metabolic syndrome risk factors in obese adolescents with regard to the effect size (ES). Both periodization models presented a large effect on muscular endurance. Despite the limitation of sample size, our results suggested that the ACE genotype may influence the functional and metabolic characteristics of obese adolescents and may be considered in the future strategies for massive obesity control.
Idioma Inglês
Financiador AFIP
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Número do financiamento FAPESP: 2006/00684-3
FAPESP: 2008/53069-0
FAPESP: 9814303-3
Data 2010-04-01
Publicado em Obesity. New York: Nature Publishing Group, v. 18, n. 4, p. 766-772, 2010.
ISSN 1930-7381 (Sherpa/Romeo, fator de impacto)
Editor Nature Publishing Group
Extensão 766-772
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000276665200020

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