Multivariate Analysis of Risk Factors for Early Loss of Pancreas Grafts Among Simultaneous Pancreas-Kidney Transplants

Multivariate Analysis of Risk Factors for Early Loss of Pancreas Grafts Among Simultaneous Pancreas-Kidney Transplants

Author Sousa, M. G. Autor UNIFESP Google Scholar
Linhares, M. M. Autor UNIFESP Google Scholar
Gonzalez, A. M. Autor UNIFESP Google Scholar
Rangel, E. B. Autor UNIFESP Google Scholar
Melaragno, C. Autor UNIFESP Google Scholar
Sa, J. R. Autor UNIFESP Google Scholar
Salzedas, A. A. Autor UNIFESP Google Scholar
Nishimi, A. Y. Autor UNIFESP Google Scholar
Lopes Filho, G. J. Autor UNIFESP Google Scholar
Matos, D. Autor UNIFESP Google Scholar
Pestana, J. O. M. Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract To evaluate the risk factors for pancreas graft loss within 3 months postoperatively among 170 simultaneous pancreas kidney transplantation (SPKT) we examined 38 variables.Methods. Twenty-two variables were related to recipients; 12 to donors and 4 to the surgical procedure. in addition the latest follow-up dates as well as the transplant and/or death dates. Independent variables were examined with reference to the dependent pancreatic loss variable, excluding losses owing to deaths. Variables with statistical significance were analyzed to predict early graft loss.Results. Univariate analyses determined the following significant variables: kidney cold ischemia time, older donors, non-white donors, death cause related to vascular disease, wound infection, and length of extended hospitalization. However, multivariate analysis showed that only donor age and kidney cold ischemia time were significant predictors for early pancreastic graft loss.Conclusion. Donor age and kidney cold ischemia time were independently related to pancreatic loss after SPKT within 3 months posttransplantation.
Language English
Date 2010-03-01
Published in Transplantation Proceedings. New York: Elsevier B.V., v. 42, n. 2, p. 547-551, 2010.
ISSN 0041-1345 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 547-551
Origin http://dx.doi.org/10.1016/j.transproceed.2010.01.044
Access rights Closed access
Type Article
Web of Science ID WOS:000276051400039
URI http://repositorio.unifesp.br/handle/11600/32355

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