alpha-Arylation and Alkynylation of Cyclic alpha-Iodoenones Using Palladium-Catalyzed Cross-Coupling Reactions with Trifluoroborate Salts

alpha-Arylation and Alkynylation of Cyclic alpha-Iodoenones Using Palladium-Catalyzed Cross-Coupling Reactions with Trifluoroborate Salts

Author Gueogjian, Kemilla Google Scholar
Singh, Fateh V. Google Scholar
Pena, Jesus M. Google Scholar
Amaral, Monica F. Z. J. Google Scholar
Stefani, Helio A. Autor UNIFESP Google Scholar
Institution Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Abstract An expeditious synthesis of alpha-aryl- and alpha-alkynylcyclo-hexenones is described and illustrated by palladium-catalyzed cross-coupling reaction of cyclic alpha-iodoenones with potassium aryltrifluoroborate salts. This procedure offers easy access to alpha-arylated and alkynylated cyclohexenones functionalized with electrondonor and -acceptor substituents in good yields.
Keywords cross-coupling reaction
cyclic alpha-iodoenones
alpha-substituted enones
Language English
Sponsor Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Grant number FAPESP: 07/59404-2
FAPESP: 07/51466-9
FAPESP: 09/50380-2
CNPq: 300.613/2007-5
Date 2010-02-01
Published in Synlett. Stuttgart: Georg Thieme Verlag Kg, n. 3, p. 427-432, 2010.
ISSN 0936-5214 (Sherpa/Romeo, impact factor)
Publisher Georg Thieme Verlag Kg
Extent 427-432
Origin http://dx.doi.org/10.1055/s-0029-1218580
Access rights Closed access
Type Article
Web of Science ID WOS:000274233900017
URI http://repositorio.unifesp.br/handle/11600/32239

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