Prevalence of Acne Vulgaris in Patients with Down Syndrome

Prevalence of Acne Vulgaris in Patients with Down Syndrome

Author Bagatin, Edileia Autor UNIFESP Google Scholar
Leao Kamamoto, Cristhine Souza Autor UNIFESP Google Scholar
Santos Guadanhim, Lilia Ramos dos Autor UNIFESP Google Scholar
Sanudo, Adriana Google Scholar
Dias, Marilia Costa Google Scholar
Barraviera, Isa Mara Google Scholar
Colombo, Fernanda Consolim Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Assoc Pais & Amigos Excepcionais
Abstract Background/Objective: Acne vulgaris exhibits a worldwide prevalence of up to 95% among adolescents. On the other hand, Down syndrome is an autosomal chromosomal disorder with associated dermatoses and a tendency to obesity. There are no data on its association with acne. Our aim was to detect the prevalence of acne, its forms and associated factors in Down syndrome. Method: A cross-sectional study including 89 subjects aged 10-28 years from Associacao de Pais e Amigos dos Excepcionais-São Paulo to verify acne, metabolic and hormonal disorders by interview, clinical and laboratory examinations. Results: We evaluated 49 (55%) males and 40 (45%) females. A weak agreement between self-estimation for acne and examination result was detected. the overall prevalence of acne was 70.8%: 83.7% in males and 55% in females. the prevalence of acne in the age groups 10-17 and 18-28 was 62 and 78.7%, respectively. Facial comedonal acne was mostly detected. the prevalence of obesity was 40%, that of metabolic disorders 7% and that of hyperandrogenism (in females) 15%. Except for gender, no other factor evaluated correlated with acne. Conclusion: A low prevalence of acne in Down syndrome, a predominance in males aged 18-28 and a facial comedonal form were detected. An association with obesity, metabolic disorders or hyperandrogenemia was not assessed. Copyright (C) 2010 S. Karger AG, Basel
Keywords Acne vulgaris
Down syndrome
Language English
Sponsor Stiefel Institute, São Paulo, Brazil
Date 2010-01-01
Published in Dermatology. Basel: Karger, v. 220, n. 4, p. 333-339, 2010.
ISSN 1018-8665 (Sherpa/Romeo, impact factor)
Publisher Karger
Extent 333-339
Access rights Closed access
Type Article
Web of Science ID WOS:000279331500009

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