Twelve years of coccidioidomycosis in Ceara State, Northeast Brazil: epidemiologic and diagnostic aspects

Twelve years of coccidioidomycosis in Ceara State, Northeast Brazil: epidemiologic and diagnostic aspects

Author Cordeiro, Rossana de Aguiar Google Scholar
Nogueira Brilhante, Raimunda Samia Google Scholar
Gadelha Rocha, Marcos Fabio Google Scholar
Bandeira, Silviane Praciano Google Scholar
Bezerra Fechine, Maria Auxiliadora Google Scholar
Camargo, Zoilo Pires de Autor UNIFESP Google Scholar
Costa Sidrim, Jose Julio Google Scholar
Institution Univ Estadual Ceara
Univ Fed Ceara
Universidade Federal de São Paulo (UNIFESP)
Abstract Coccidioidomycosis is an endemic infection in the Americas caused by the dimorphic fungi Coccidioides immitis and Coccidioides posadasii. Although the disease occurs in Brazil in sporadic form, little information about these cases is available. in this study, we summarize the most important clinical, epidemiologic, and diagnostic features of coccidioidomycosis in Ceara State (Northeast Brazil) during the past 12 years. in this period, 19 cases of coccidioidomycosis were diagnosed. All the patients were young males and came from semiarid areas of the state. the majority of cases were associated to armadillo hunting, and pulmonary disease was the most common clinical presentation. in our laboratory, coccidioidomycosis was confirmed by culture, serology, and polymerase chain reaction tests, which together were very suitable for the diagnosis of this disease. Based on our local experience, we believe many cases of this disease are misdiagnosed or not diagnosed in our region. Therefore, some strategies for improvement of diagnosis should be encouraged by local authorities. (C) 2010 Elsevier Inc. All rights reserved.
Keywords Coccidioidomycosis
Diagnosis
Epidemiology
Brazil
Language English
Sponsor Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Grant number CNPq: 620161/2006-0
FAPESP: 04/14270-0
Date 2010-01-01
Published in Diagnostic Microbiology and Infectious Disease. New York: Elsevier B.V., v. 66, n. 1, p. 65-72, 2010.
ISSN 0732-8893 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 65-72
Origin http://dx.doi.org/10.1016/j.diagmicrobio.2008.09.016
Access rights Closed access
Type Article
Web of Science ID WOS:000277576800009
URI http://repositorio.unifesp.br/handle/11600/32093

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