Prevalence of serological markers of hepatitis B virus in pregnant women from Paraná State, Brazil

Prevalence of serological markers of hepatitis B virus in pregnant women from Paraná State, Brazil

Autor Bertolini, D.a. Google Scholar
Pinho, J.r.r. Google Scholar
Saraceni, C.p. Google Scholar
Moreira, R.c. Google Scholar
Granato, Celso Francisco Hernandes Autor UNIFESP Google Scholar
Carrilho, F.j. Google Scholar
Instituição Universidade Estadual de Maringá Departamento de Análises Clínicas Laboratório de Imunologia Clínica
Universidade de São Paulo (USP)
Instituto Adolfo Lutz Serviço de Virologia
Universidade Federal de São Paulo (UNIFESP)
Resumo The prevalence of hepatitis B virus (HBV) in Brazil increases from South to North but moderate to elevated prevalence has been detected in the Southwest of Paraná State. The prevalence of serological markers of HBV was evaluated in 3188 pregnant women from different counties in Paraná State and relevant epidemiological features were described. The prevalence of HBV markers in pregnant women for the state as a whole was 18.5% (95% CI = 17.2-19.9), ranging from 7.2% in Curitiba to 38.5% in Francisco Beltrão. The endemicity of HBV marker prevalence in pregnant women was intermediate in Cascavel, Foz do Iguaçu, and Francisco Beltrão, and low in Curitiba, Londrina, Maringá, and Paranaguá. Multiple logistic regression showed that HBV marker prevalence increased with age, was higher among black women, among women of Italian and German descent, and among women who had family members in neighboring Rio Grande do Sul State. Univariate analysis showed that HBV marker prevalence was also higher among women with no education or only primary education, with a lower family income and whose families originated from the South Region of Brazil. Pregnant women not having positive HBV markers (anti-HBc, HBsAg or anti-HBs detected by ELISA) corresponded to 73.7% of the population studied, implying that HBV vaccination needs to be reinforced in Paraná State. The highest prevalence was found in three counties that received the largest number of families from Santa Catarina and Rio Grande do Sul, where most immigrants were of German or Italian ascendance. This finding probably indicates that immigrants that came to this area brought HBV infection to Southwestern Paraná State.
Palavra-chave Hepatitis B virus
Serological markers
Pregnant women
Idioma Inglês
Data de publicação 2006-08-01
Publicado em Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 39, n. 8, p. 1083-1090, 2006.
ISSN 0100-879X (Sherpa/Romeo, fator de impacto)
Publicador Associação Brasileira de Divulgação Científica
Extensão 1083-1090
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000239936900011
SciELO S0100-879X2006000800011 (estatísticas na SciELO)
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