Serologic Detection of Coccidioidomycosis Antibodies in Northeast Brazil

Serologic Detection of Coccidioidomycosis Antibodies in Northeast Brazil

Author Cordeiro, Rossana de Aguiar Google Scholar
Bezerra Fechine, Maria Auxiliadora Google Scholar
Nogueira Brilhante, Raimunda Samia Google Scholar
Gadelha Rocha, Marcos Fabio Google Scholar
Freire da Costa, Ana Karoline Google Scholar
Tiemi Dias Nagao, Maria Aparecida Google Scholar
Camargo, Zoilo Pires de Autor UNIFESP Google Scholar
Costa Sidrim, Jose Julio Google Scholar
Institution Univ Fed Ceara
Univ Estadual Ceara
Universidade Federal de São Paulo (UNIFESP)
Abstract Coccidioidomycosis is a systemic infection caused by Coccidioides spp. the disease is endemic in Brazil but its incidence is underreported as it is not a notifiable disease. This article presents the results of a serologic survey carried out with 229 volunteers in northeast Brazil by the immunodiffusion (ID) test with commercial Coccidioides spp. antigens. the commercial ID test detected 15 individuals without clinical diagnosis of the disease and two individuals in treatment for coccidioidomycosis. Regarding the epidemiological data, most of the positive individuals were male, between 18 and 65 years of age and were engaged in armadillo hunting. Three women who had never participated in armadillo hunts also displayed positive results for coccidioidal antibodies. Besides armadillo hunts, exposure to environmental dust in endemic areas may account for the serologic response detected in the study. the data from this study suggest the importance of performing epidemiological surveys for coccidioidomycosis in order to understand the prevalence of this disease in Brazil.
Keywords Coccidioidomycosis
Serologic survey
Language English
Sponsor Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Grant number CNPq: 620161/2006-0
FAPESP: 04/14270-0
Date 2009-04-01
Published in Mycopathologia. Dordrecht: Springer, v. 167, n. 4, p. 187-190, 2009.
ISSN 0301-486X (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 187-190
Access rights Closed access
Type Article
Web of Science ID WOS:000264549100003

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