Epstein-Barr virus detection in invasive and pre-invasive lesions of the uterine cervix

Show simple item record

dc.contributor.author Santos, Nelly Beatriz Modos [UNIFESP]
dc.contributor.author Villanova, Fabiola Elizabeth
dc.contributor.author Andrade, Priscila Maria
dc.contributor.author Ribalta, Julisa [UNIFESP]
dc.contributor.author Focchi, José [UNIFESP]
dc.contributor.author Otsuka, Audrey Yumi
dc.contributor.author Silva, Ismael Dale [UNIFESP]
dc.date.accessioned 2016-01-24T13:52:13Z
dc.date.available 2016-01-24T13:52:13Z
dc.date.issued 2009-02-01
dc.identifier http://dx.doi.org/10.3892/or_00000236
dc.identifier.citation Oncology Reports. Athens: Spandidos Publ Ltd, v. 21, n. 2, p. 403-405, 2009.
dc.identifier.issn 1021-335X
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/31274
dc.description.abstract In the present study, our aim was to investigate whether EBV DNA could be found in association with invasive and pre-invasive cervical cancer lesions. We hypothesize that EBV is not merely a commensal agent when present in malignant cervical lesions. DNA was extracted from cervical scrapings followed by nested PCR-based amplification. the patients were 66 women with high grade cervical intraepithelial neoplasia and 14 women with invasive cervical cancer. the control group consisted of 89 women with a normal Pap smear and colposcopy as well as a negative HPV DNA test. Analysis of our results, in conjunction with the work of other authors, leads us to propose that EBV is not merely a commensal agent when present in malignant cervical lesions. the presence of DNA from EBV is significantly associated with cervical cancer. en
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent 403-405
dc.language.iso eng
dc.publisher Spandidos Publ Ltd
dc.relation.ispartof Oncology Reports
dc.rights Acesso aberto
dc.subject Epstein-Barr virus en
dc.subject cervical cancer en
dc.subject HPV en
dc.title Epstein-Barr virus detection in invasive and pre-invasive lesions of the uterine cervix en
dc.type Artigo
dc.contributor.institution Universidade de São Paulo (USP)
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Univ São Paulo, Dept Urol, Urol Lab LIM55, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Gynecol, Colposcopy Sect, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Mol Gynecol Lab, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Gynecol, Colposcopy Sect, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Mol Gynecol Lab, São Paulo, Brazil
dc.description.sponsorshipID FAPESP: 99/03366-6
dc.identifier.doi 10.3892/or_00000236
dc.description.source Web of Science
dc.identifier.wos WOS:000262679300019



File

File Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

Search


Browse

Statistics

My Account