Effects of hormone therapy with estrogen and/or progesterone on sleep pattern in postmenopausal women

Effects of hormone therapy with estrogen and/or progesterone on sleep pattern in postmenopausal women

Autor Hachul, Helena Autor UNIFESP Google Scholar
Bittencourt, Lia R. A. Autor UNIFESP Google Scholar
Andersen, Monica L. Autor UNIFESP Google Scholar
Haidar, Mauro Abi Autor UNIFESP Google Scholar
Baracat, Edmund C. Autor UNIFESP Google Scholar
Tufik, Sergio Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Objective: To investigate the effects of estrogen and progesterone on steep in postmenopausal women. Method: the 33 participants were randomly assigned to an estrogen or placebo group after undergoing clinical and hormonal assessments and a polysomnogram, and they underwent the same tests again after 12 weeks. Then, white still taking estrogen or placebo, they all received progesterone for another 12 weeks and underwent a final polysomnogram. Results: Estrogen plus progesterone was more effective than estrogen alone in decreasing the prevalence of periodic limb movement (PLM) (8.1% vs 2.8%), hot flashes (14.2% vs 0%), and bruxism (11.1% vs 0%) at night, or somnolence and attention difficulty during the day. the prevalences of breathing irregularities, arousal from steep, anxiety, and memory impairment were decreased in both groups following progesterone treatment. Conclusion: While not significantly affecting steep quality, hormone therapy decreased the prevalence of arousal in both groups and that of PLM in the group treated with estrogen plus progesterone. (c) 2008 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
Palavra-chave Estrogen
Hormone
Menopause
Periodic limb movements
Polysomnography
Progesterone
Sleep
Idioma Inglês
Financiador Associacao Fundo de Incentivo a Psicofarmacologia (AFIP)
Wyeth
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Sergio Tufik received Centro de Excelencia em Pesquisa
Inovacao e Difusao (CEPID)
Número do financiamento Inovacao e Difusao (CEPID): 98/14303-3
Data de publicação 2008-12-01
Publicado em International Journal of Gynecology & Obstetrics. Clare: Elsevier B.V., v. 103, n. 3, p. 207-212, 2008.
ISSN 0020-7292 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 207-212
Fonte http://dx.doi.org/10.1016/j.ijgo.2008.07.009
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000261920300011
Endereço permanente http://repositorio.unifesp.br/handle/11600/31074

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