Outcome following lumbar disc surgery: the role of fibrosis

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dc.contributor.author Almeida, Daniel Benzecry [UNIFESP]
dc.contributor.author Prandini, Mirto Nelson [UNIFESP]
dc.contributor.author Awamura, Yumi
dc.contributor.author Vitola, Maria Luiza
dc.contributor.author Simiao, Monica Pedro
dc.contributor.author Milano, Jeronimo Buzetti
dc.contributor.author Bordignon, Kelly Cristina
dc.contributor.author Ache, Mariane Pastuch
dc.contributor.author Ramina, Ricardo
dc.date.accessioned 2016-01-24T13:51:50Z
dc.date.available 2016-01-24T13:51:50Z
dc.date.issued 2008-11-01
dc.identifier http://dx.doi.org/10.1007/s00701-008-0131-2
dc.identifier.citation Acta Neurochirurgica. Wien: Springer Wien, v. 150, n. 11, p. 1167-1176, 2008.
dc.identifier.issn 0001-6268
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/30993
dc.description.abstract Failed-back surgery syndrome remains a challenge for spinal surgeons. It can be related to several causes, including poor surgical indication, misdiagnosis, surgical technique failure, spondilodiscitis and fibrosis. Fibrosis has been associated with a poorer outcome in lumbar disc surgery, although its role in the generation of symptoms is not yet clear. in this study, the authors have analyzed any possible correlation between the clinical outcome and the degree of fibrosis.Forty consecutive patients were enrolled in a prospective study. All of them had operations in the lower lumbar disc in a single level for the first time. Three months after the operation they were submitted to clinical outcome evaluations and questionnaires, including Numeric Pain Rating scales (NPR) for lumbar and leg pain, the McGill Pain Questionnaire, the Quebec Back Pain Disability scale (QBPD) and Straight Leg Raising test. These data were correlated with the degree of fibrosis as revealed by Magnetic Resonance Imaging (MRI).After 3 months, the NPR values for lumbar and leg pain ranged from 0 to 8 (mean 2.32 and 1.67 respectively). the values of the post-operative QBPD scale ranged from 1 to 71 (mean 25.9). Every patient showed a varied degree of fibrosis on MRI. However, statistical analysis depicted no significant correlation between fibrosis and a poorer clinical outcome for pain and disability.The authors found no correlation between excessive fibrosis with lumbar and leg pain, disability or straight leg resistance. the role of fibrosis in the generation of symptoms in patients who have had lumbar disc surgery should be reevaluated. en
dc.format.extent 1167-1176
dc.language.iso eng
dc.publisher Springer
dc.relation.ispartof Acta Neurochirurgica
dc.rights Acesso restrito
dc.subject Lumbar disc en
dc.subject Fibrosis en
dc.subject Surgery en
dc.subject Magnetic resonance imaging en
dc.subject Failed-back en
dc.title Outcome following lumbar disc surgery: the role of fibrosis en
dc.type Resenha
dc.rights.license http://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.contributor.institution Inst Neurol Curitiba
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution CEDIP
dc.description.affiliation Inst Neurol Curitiba, CINDOR, BR-80730060 Curitiba, Parana, Brazil
dc.description.affiliation Universidade Federal de São Paulo, São Paulo, Brazil
dc.description.affiliation CEDIP, Curitiba, Parana, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, São Paulo, Brazil
dc.identifier.doi 10.1007/s00701-008-0131-2
dc.description.source Web of Science
dc.identifier.wos WOS:000260834800008


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