Plasmid-mediated quinolone resistance in Aeromonas allosaccharophila recovered from a Swiss lake

Plasmid-mediated quinolone resistance in Aeromonas allosaccharophila recovered from a Swiss lake

Autor Picão, Renata Cristina Autor UNIFESP Google Scholar
Poirel, Laurent Google Scholar
Demarta, Antonella Google Scholar
Ferreira Silva, Carla Sofia Google Scholar
Rita Corvaglia, Anna Google Scholar
Petrini, Orlando Google Scholar
Nordmann, Patrice Google Scholar
Instituição Hop Bicetre
Univ Paris Sud
Universidade Federal de São Paulo (UNIFESP)
Ist Cantonale Microbiol
Univ Geneva
Resumo Objectives: To search for plasmid-mediated qnr genes among waterborne environmental Aeromonas spp. recovered from Switzerland.Methods: Isolates presenting MICs of nalidixic acid or ciprofloxacin >= 1 mg/L were screened for qnr genes by a multiplex PCR approach followed by sequencing. Plasmids were transferred by transformation, and further analysis of the genetic structures surrounding the qnrS2 gene was carried out by PCR and sequencing.Results: A qnrS2 gene was identified from a single Aeromonas allosaccharophila isolate (Lugano lake, Lugano), as part of a mobile insertion cassette located on a broad host range IncU-type plasmid. This plasmid co-harboured a class 1 integron containing the aac(6 ')-Ib-cr, bla(OXA-1), catB3 and arr-3 gene cassettes.Conclusions: These findings strengthen further the role of Aeromonas spp. as a reservoir of antimicrobial resistance determinants in the environment.
Palavra-chave A. allosaccharophila
QnrS2
environment
Idioma Inglês
Financiador Ministere de l'Education Nationale et de la Recherche
Universite Paris XI, France
Swiss National Science Foundation
National Research Program 'Antibiotic resistance'
European Community
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
PDEE
Número do financiamento Ministere de l'Education Nationale et de la Recherche: UPRES-EA3539
National Research Program 'Antibiotic resistance': NRP49
European Community: DRESP2
European Community: LSHM-CT-2005-018705
PDEE: 3682/07-2
Data de publicação 2008-11-01
Publicado em Journal of Antimicrobial Chemotherapy. Oxford: Oxford Univ Press, v. 62, n. 5, p. 948-950, 2008.
ISSN 0305-7453 (Sherpa/Romeo, fator de impacto)
Publicador Oxford Univ Press
Extensão 948-950
Fonte http://dx.doi.org/10.1093/jac/dkn341
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000259974700017
Endereço permanente http://repositorio.unifesp.br/handle/11600/30979

Exibir registro completo




Arquivo

Arquivo Tamanho Formato Visualização

Não existem arquivos associados a este item.

Este item está nas seguintes coleções

Buscar


Navegar

Minha conta